Hematologic Malignancies

Case Studies in Cytogenetic and Molecular Genetics

Authors: Bhargava, Manorama

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  • Explains the significance of the results obtained towards the prognosis and treatment response
  • Presents several case studies in hematologic malignancies with particular reference to cytogenetics
  • Describes a vision of future development towards enhancing diagnosis and application of targeted therapies
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eBook 128,39 €
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  • ISBN 978-981-334-799-1
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Hardcover 166,39 €
price for Spain (gross)
  • ISBN 978-981-334-798-4
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  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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About this book

This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail.  The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.

About the authors

Dr. Bhargava has served as a Professor and Head, Department of Hematology at the prestigious All India Institute of Medical Sciences until September 2001, Sir Ganga Ram Hospital till 2016 and as Senior Advisor and Head Hematopathology at Medanta, The Medicity until May 2020.

Dr. Bhargava is a pioneer in Hematology in India and is widely recognised for her contributions to Hematology both nationally and internationally.  In a career spanning almost 50 years, she advocated and brought awareness for hematology as a discipline separate from Internal Medicine and Pathology where it constituted a minor part.  Recipient of prestigious fellowships such as Alexander Von Humboldt, Fogarty and INSA fellowships. She has been principal investigator on several research grants, notably Indo-US, Indo-French, Indo–German and Indo-Japan grants and has published more than 300 articles in national and international journals.

In recognition of her contributions to Hematology, she was awarded the Dr. B.C. Roy National Award and the highest award of Indian Council of Medical Research, the Basanti Devi Amirchand prize. An acclaimed teacher, she established the first  ever superspecialty degrees of DM in clinical Hematology and DM in Hematapathology in the year 2000 at the All India Institute of Medical Sciences and the Diplomate National Board in Hematology in 2008.

Reviews

“The audience for this book would include trainees and practitioners in hematology-oncology and hematopathologists. The book provides a good overview of approaches to laboratory diagnosis of hematologic malignancies. … this technique is useful because identification of certain mutations may dictate unique treatment options.” (George M Rodgers, Doody's Book Reviews, May 14, 2021)


Table of contents (11 chapters)

Table of contents (11 chapters)

Buy this book

eBook 128,39 €
price for Spain (gross)
  • ISBN 978-981-334-799-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 166,39 €
price for Spain (gross)
  • ISBN 978-981-334-798-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Hematologic Malignancies
Book Subtitle
Case Studies in Cytogenetic and Molecular Genetics
Authors
Copyright
2021
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-334-799-1
DOI
10.1007/978-981-33-4799-1
Hardcover ISBN
978-981-334-798-4
Edition Number
1
Number of Pages
XXVI, 246
Number of Illustrations
118 b/w illustrations, 114 illustrations in colour
Topics