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Pathogenicity and Drug Resistance of Human Pathogens

Mechanisms and Novel Approaches

  • Focus on the cutting-edge research on the pathogens that are involved in bacterial, viral, protozoan, and fungal infections
  • Helps in understanding the pathogenesis and drug-resistance mechanisms of the microbial infections
  • Entails the current research and future perspective of the diagnostics and novel targets against these pathogens
  • Highlights the application of bioinformatics and nanobiotechnology in the treatment of the microbial infections

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xxiv
  2. Pathogenicity and Drug Resistance in Mycobacterium tuberculosis

    1. Front Matter

      Pages 1-1
    2. The Challenge of Drug-Resistant Tuberculosis: An Update

      • Chanchal Kumar, Kamal Shrivastava, Shraddha Gupta, Mandira Varma-Basil
      Pages 33-56
    3. Eliminating Mycobacterial Persistence: Novel Targets for Anti-TB Therapy

      • Ashima Bhaskar, Ved Prakash Dwivedi, Vinay Kumar Nandicoori
      Pages 57-79
    4. Roadmap for the Eradication of Multidrug Resistant Tuberculosis

      • Mohit Agarwal, Ashok Rattan
      Pages 93-107
  3. Candida Infections and Therapeutic Strategies

    1. Front Matter

      Pages 109-109
    2. Fungal Diseases and Their Treatment: A Holistic Approach

      • Sushil Kumar, Tushar Jain, Dibyendu Banerjee
      Pages 111-134
    3. Role of Mitochondria in Fungal Drug Resistance

      • Ritu Pasrija, Deepika Kundu
      Pages 147-164
  4. Malaria Parasite Biology

    1. Front Matter

      Pages 179-179
    2. Road Towards Development of New Antimalarial: Organelle Associated Metabolic Pathways in Plasmodium as Drug Targets and Discovery of Lead Drug Candidates

      • Mohd Asad, Azhar Muneer, Pradeep Kumar, Vandana Thakur, Sumit Rathore, Pawan Malhotra et al.
      Pages 181-211
    3. Cellular Homoeostasis and Cell Signalling in Malaria Parasite: Role of Autophagy

      • Azhar Muneer, Shweta Singh, Monika Narwal, Pawan Malhotra, Asif Mohmmed, Sumit Rathore
      Pages 213-230
  5. Emerging Viral Diseases

    1. Front Matter

      Pages 231-231
    2. Prion Diseases: A Concern for Mankind

      • Syed Beenish Rufai, Ayush Gupta, Sarman Singh
      Pages 283-302
  6. Translational Research in Human Microbes

    1. Front Matter

      Pages 303-303

About this book

The book comprehensively discusses the mechanisms of pathogenesis and drug resistance; current diagnostics landscape of four key human pathogens; bacterial, fungal, protozoans and viral which are the causes of major infectious diseases. It also assesses the emerging technologies for the detection and quantification of these pathogens. Further, it discusses the novel opportunities to fight against these infectious diseases and to identify pertinent drug targets with novel methodologies. It also reviews the current and future insights into the control, elimination, and eradication of these infectious diseases.

Importantly, the book discusses the epidemiological characteristics and various challenges in combating Ebola and Influenza diseases. Finally, the book highlights the growing role of nanotechnology and bioinformatics resources for combating the infectious diseases.

In summary, the book provides the mechanistic insight of the pathogenicity, drug-resistance,therapeutic strategies and identification of the novel drug targets of Mycobacterium tuberculosis, Plasmodium, Candida, Hepatitis C and emerging viral infections.


Editors and Affiliations

  • Amity Institute of Biotechnology, Amity University Haryana, Manesar, Gurugram, India

    Saif Hameed, Zeeshan Fatima

About the editors

Dr. Saif Hameed is currently Associate Professor at Amity Institute of Biotechnology, Amity University Haryana. Dr. Hameed did his Bachelors from University of Delhi and Masters from Jamia Hamdard with distinction in 2003 and 2005 respectively. He completed his doctoral studies in Life Sciences from Jawaharlal Nehru University in 2010 where he also received CSIR Research Associateship for the one year postdoctoral work. He also worked as Visiting Scholar in Institute für Mikrobiologie, Heinrich-Heine-Universität, Düsseldorf, Germany in 2008. Dr. Hameed has received Young Scientist award from Science and Engineering Research Board, Department of Science and Technology, New Delhi in the year 2012. Dr. Hameed is actively engaged in research in the field of infectious diseases related to multidrug resistance (MDR) in pathogenic fungi. He has around 40 peer-reviewed papers to his credit in both international and national journals of repute, 2 books, 15 book chaptersalong with 22 popular articles with 2 of them as ‘cover story’. He has successfully convened 7 national conferences as Organizing Secretary. He has guided 2 Ph.D. students for their doctoral degrees and supervised 20 UG & PG level students for their research projects. He is life member of Association of Microbiologist of India (AMI) and International Society for Infectious Diseases (ISID).

 

Dr. Zeeshan Fatima is currently working as Associate Professor at Amity Institute of Biotechnology, Amity University Haryana. Dr. Fatima did her Bachelors and Masters from Banaras Hindu University in 2000 and 2002 respectively. She earned her doctoral degree in Biochemistry from Aligarh Muslim University in 2008. She has held research positions under nationally and internationally funded research projects which also include her Research Associateship at B.H.U. and J.N.U. and postdoctoral training from University of Cincinnati, Ohio, USA in 2010. Dr. Fatima hasreceived two Young Scientist awards under Fast Track and Women Scientist Schemes respectively from Science and Engineering Research Board, Department of Science and Technology, New Delhi in the year 2012.  She has also bagged regular projects for funding from DBT, Board of Research in Nuclear Sciences (BRNS), BARC Mumbai and Ministry of AYUSH, New Delhi. She is actively engaged in research in the field of infectious diseases and particularly on the aspect of Multidrug resistance in human pathogen Mycobacterium tuberculosis and Candida albicans. She has 2 books and around 35 peer-reviewed papers to her credit in both international and national journals of repute. She participated in several international and national conferences and received various accolade in the form of best paper awards. She has successfully convened 5 national conferences as Organizing Secretary and organized many guest lectures. She has supervised 2 Ph.D. students and guided21 UG & PG level students for their research projects. She is life member of Association of Microbiologist of India (AMI) and International Society for Infectious Diseases (ISID).


Bibliographic Information

  • Book Title: Pathogenicity and Drug Resistance of Human Pathogens

  • Book Subtitle: Mechanisms and Novel Approaches

  • Editors: Saif Hameed, Zeeshan Fatima

  • DOI: https://doi.org/10.1007/978-981-32-9449-3

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Hardcover ISBN: 978-981-32-9448-6Published: 24 January 2020

  • Softcover ISBN: 978-981-32-9451-6Published: 26 August 2021

  • eBook ISBN: 978-981-32-9449-3Published: 23 January 2020

  • Edition Number: 1

  • Number of Pages: XXIV, 404

  • Number of Illustrations: 9 b/w illustrations, 43 illustrations in colour

  • Topics: Parasitology, Infectious Diseases, Drug Resistance, Bioinformatics, Virology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access