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Advances in Experimental Medicine and Biology

Tau Biology

Editors: Takashima, Akihiko, Wolozin, Benjamin, Buee, Luc (Eds.)

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  • Presents expert opinions and up-to-date studies on tau
  • Provides new insights into the tau molecule and tauopathies
  • Offers inspiration for development of effective therapies
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eBook 160,49 €
price for Spain (gross)
  • ISBN 978-981-329-358-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 207,99 €
price for Spain (gross)
About this book

This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons.  In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons.  Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death.  With the help of new technologies, researchers are now solving these long-standing questions.  In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.


About the authors

Akihiko Takashima

Gakushuin University, Dept Life Sci., Lab Alzheimers Dis., Japan


Benjamin Wolozin

Boston University, School of Med., Dept Pharmacol., USA


Luc Buee

University of Lille, CHU Lille, INSERM, Memory & Resources Res. Ctr., France



Table of contents (30 chapters)

Table of contents (30 chapters)

Buy this book

eBook 160,49 €
price for Spain (gross)
  • ISBN 978-981-329-358-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 207,99 €
price for Spain (gross)
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Bibliographic Information

Bibliographic Information
Book Title
Tau Biology
Editors
  • Akihiko Takashima
  • Benjamin Wolozin
  • Luc Buee
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1184
Copyright
2019
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-329-358-8
DOI
10.1007/978-981-32-9358-8
Hardcover ISBN
978-981-329-357-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XI, 416
Number of Illustrations
8 b/w illustrations, 75 illustrations in colour
Topics