Skip to main content
SpringerLink
Log in
Book cover

Multiple Action-Based Design Approaches to Antibacterials

  • Book
  • © 2021

Overview

Authors:
  1. John Bremner

    1. School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, Australia

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • Provides readers with suggestions for further research using specific examples as starting points in the design process – for example, the antibacterial alkaloid berberine
  • Includes a comparative section relating combinations, hybrids, and pro-drug features which will assist further developments in the field
  • Suggests for pathways to refine some illustrative hypothetical molecular examples in order to bring them closer to experimental testing

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (5 chapters)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Antibacterials

    • John Bremner
    Pages 1-20

  3. Antibacterial Combinations

    • John Bremner
    Pages 21-49

  4. Single Molecule Non-cleavable Multiply Active Antibacterials

    • John Bremner
    Pages 51-119

  5. Design Principles and Development of Prodrugs for Multiply Active Antibacterials

    • John Bremner
    Pages 121-158

  6. Future Possibilities

    • John Bremner
    Pages 159-187

  7. Back Matter

    Pages 189-193
    Download chapter PDF
Back to top

Keywords

About this book

This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development. 

Authors and Affiliations

  • School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, Australia

    John Bremner

About the author

John Bremner was born in Perth, Western Australia and after completion of his undergraduate studies at the University of Western Australia he undertook a PhD at the Australian National University. After a further year at Harvard University as a Research Fellow he returned to Australia to take up a Lectureship in Chemistry at the University of Tasmania. Later, on sabbatical leave, he completed a Diploma in Chemical Pharmacology at the University of Edinburgh. In 1991 he was appointed as Professor of Organic Chemistry at the University of Wollongong in NSW, Australia. He retired in 2007 and is now an Emeritus Professor of the University of Wollongong. He is a Fellow of The Royal Australian Chemical Institute and received a Distinguished Fellow Award of the RACI in 2011. In 2001 he received the Adrien Albert Award in medicinal chemistry. He is also a Fellow of the Royal Society of Chemistry.

Bibliographic Information

  • Book Title: Multiple Action-Based Design Approaches to Antibacterials

  • Authors: John Bremner

  • DOI: https://doi.org/10.1007/978-981-16-0999-2

  • Publisher: Springer Singapore

  • eBook Packages: Engineering, Engineering (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2021

  • Hardcover ISBN: 978-981-16-0998-5Published: 06 April 2021

  • Softcover ISBN: 978-981-16-1001-1Published: 07 April 2022

  • eBook ISBN: 978-981-16-0999-2Published: 05 April 2021

  • Edition Number: 1

  • Number of Pages: XIII, 193

  • Number of Illustrations: 93 b/w illustrations, 10 illustrations in colour

  • Topics: Biochemical Engineering, Theoretical and Computational Chemistry, Medicinal Chemistry, Microbiology

Publish with us

Policies and ethics

Back to top

Search

Navigation