Overview
- Discusses the successes and critically assesses the failures of new drug discovery efforts
- Shares insights and updates on drug development in a wide range of areas such as metabolic diseases, parasitic diseases, cancer, and microbial diseases
- Offers an inside view of the history of drug discovery in the Indian pharmaceutical industry
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Table of contents (13 chapters)
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Front Matter
Keywords
About this book
Editors and Affiliations
About the editor
Dr Madhu Dikshit, a highly respected researcher and former Director of the CSIR-Central Drug Research Institute, Lucknow, India, has made significant contributions to the general area of Molecular Pharmacology with a special interest in redox biology. Dr Dikshit’s research has impacted the area of neutrophil biology by enhancing our understanding of e.g. chemotaxis, phagocytosis, apoptosis and also differentiation. Her pioneering work has helped identify the molecular mechanisms involved in the translocation of Nitric Oxide Synthase to the phagosomal compartment and the inflammatory potential of neutrophil extracellular traps. At the CSIR-CDRI, she initiated and led the successful anti-thrombotic drug discovery program, in the context of which two new chemical entities advanced to the pre-clinical stage and one has recently received approval for Phase I clinical trials. Dr Dikshit has published more than 170 papers in peer-reviewed journals, holds eight patents and has supervised more than 30 PhD students. Presently she is the National Chair at Translational Health Sciences & Technology Institute (THSTI), Faridabad and heads its Non-Communicable Disease Program.
Bibliographic Information
Book Title: Drug Discovery and Drug Development
Book Subtitle: The Indian Narrative
Editors: Madhu Dikshit
DOI: https://doi.org/10.1007/978-981-15-8002-4
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2021
Hardcover ISBN: 978-981-15-8001-7Published: 11 February 2021
Softcover ISBN: 978-981-15-8004-8Published: 11 February 2022
eBook ISBN: 978-981-15-8002-4Published: 10 February 2021
Edition Number: 1
Number of Pages: XIII, 376
Number of Illustrations: 147 b/w illustrations, 44 illustrations in colour
Topics: Pharmacology/Toxicology, Biotechnology, Biomedicine, general