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Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing

  • The book comprehensively describes the most recent methods for immunodiagnostics

  • It compiles the latest information on the application of immunodiagnosis in the various areas of Biomedicine

  • It elucidates the translational potential of various immunodiagnostics

  • It gives a detailed overview of the major shortcomings and the proposed troubleshooting of the technology

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-viii
  2. Biosensors for Clinical Samples: Consideration and Approaches

    • Mihaela Tertis, Oana Hosu, Anca Florea, Cecilia Cristea
    Pages 1-32
  3. Immunodiagnosis by Electrochemical Multiplexing in Clinical Samples

    • S. Campuzano, P. Yáñez-Sedeño, José M. Pingarrón
    Pages 33-59
  4. Principle and Applications of Immunodiagnostics Using Radioisotope as Tracers

    • Shishu Kant Suman, Rohit Sharma, Chandan Kumar
    Pages 61-74
  5. Redox Cycling Technologies for Point-of-Care Immunodiagnostics in Various Matrices

    • Gorachand Dutta, Despina Moschou, Riddhipratim Mandal
    Pages 75-91
  6. Next-Generation Immunosensing Technologies Based on Nano-Bio-Engineered Paper Matrices

    • Kuldeep Mahato, Budhhadev Purohit, Ashutosh Kumar, Ananya Srivastava, Pranjal Chandra
    Pages 93-110
  7. Alternative Analyte-Binding Compounds for Immunosensor-Like Point-of-Care Application

    • Ankita Kushwaha, Yuzuru Takamura, Manish Biyani
    Pages 111-124
  8. Bead-Based SELEX for Aptamers Selection and Their Application in Detection of Diverse Antigens

    • Devika N. Nagar, T. Yathirajarao, Pankaj Kumar, Pooja Kushwaha, Pankaj Suman
    Pages 125-139
  9. Changing Trends in Immunosensing Technologies and Their Commercial Aspects in Animal Health and Welfare

    • Sherin Kaul, Rajni Singh, Sharanya Kamaraju, Pankaj Suman
    Pages 141-161
  10. Methods for Enhancing Aptamer Affinity for Antigen Detection and Its Characterization

    • Komal Birader, L. Sai Keerthana, T. Yathirajarao, Jeannie Alice Barla, Pankaj Suman
    Pages 163-183
  11. Application of Biosensors to Enhance Reproductive Efficiency and Production of Livestock and Poultry by Diverse Antigen Analysis

    • Pankaj Kumar, Shalini Chakraborty, Devika Nagar, Komal Birader, Pankaj Suman
    Pages 185-194
  12. Clinical Implications of Cortisol and Bioanalytical Methods for Their Determination in Various Biological Matrices

    • Ajay Kumar Sahi, Neelima Varshney, Rakesh Kumar Sidu, Suruchi Poddar, Pallawi, Kameshwarnath Singh et al.
    Pages 195-221

About this book

This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.

Editors and Affiliations

  • Animal Biotechnology Laboratory, National Institute of Animal Biotechnology (NIAB) Hyderabad, Hyderabad, India

    Pankaj Suman

  • School of Biochemical Engineering, Indian Institute of Technology, Laboratory of Bio-Physio Sensors and Nano-bioengineering, Varanasi, India

    Pranjal Chandra

About the editors

Dr. Pankaj Suman is a Scientist and Principal Investigator at the National Institute of Animal Biotechnology, Hyderabad, India. He did his Bachelors in Veterinary Medicine from Maharashtra Animal and Fishery Sciences University, Nagpur, India and obtained the MS degree from the Indian Institute of Technology Roorkee, Roorkee, India. He did Ph.D. from the National Institute of Immunology, New Delhi. He also worked as visiting scholar at the Friedrich-Schiller University, Jena, Germany (2007-2010). His research experience spans through varying discipline of science pertaining to immunology, reproductive biology, veterinary, and clinical medicine. In the past, he has made a significant contribution in understanding the molecular mechanisms behind the immunological basis of pregnancy, vaccine delivery, and diagnostics. His current research is focused on the development of the biosensing devices for the detection of small molecules (toxins, metabolites etc.) through designing small antibodies and aptamers as a tool for detection. Till now, he has published over 25 research articles in the various reputed journals. He is the recipient of several prestigious fellowships and awards from agencies like the Council of Scientific and Industrial Research, India, Department of Science and Technology, India, United States Department of Agriculture, USA. He is also the recipient of prestigious G. P. Talwar Young Scientist award for outstanding contribution in reproductive health. He has attended several National and International conferences and delivered invited talks.

 

Dr. Pranjal Chandra is currently employed as an Assistant Professor at the School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi, India. He earned his Ph.D. from Pusan National University, South Korea and did post-doctoral training at Technion-Israel Institute of Technology, Israel. His research focus is highly interdisciplinary, spanning a wide range in biotechnology, nanobiosensors, material engineering, nanomedicine, etc. He has designed several commercially viable biosensing prototypes that can be operated for onsite analysis for biomedical diagnostics, environmental monitoring, and other point-of-care testing applications. He has published 6 books on various aspects of biosensors / medical diagnostics from IET London, Springer Nature, CRC press USA. He has also published over 85 journal articles in topmost journals of his research area including; Biosensors and Bioelectronics, Analytical Chemistry, Biomaterials, Chemical Communications, Electroanalysis, etc. His work has been greatly highlighted in over 300 topmost news agencies globally including Rajya Sabha TV, DD Science, Science Trends USA, Nature India, Vigyan Prasar, Global Medical Discovery; Canada, APBN Singapore, Business Wire; Dublin, etc. He is a recipient of many prestigious  awards and fellowships such as; DST Ramanujan fellowship (Government of India);  Early Carrier Research Award (DST, Government of India); Brain Korea -21 and National Research Foundation fellowship, South Korea; Technion post-doctoral fellowship, Israel; NMS Young scientist award, Biotech Research Society India Young Scientist Award, Young Engineers Award 2018, RSC Highly Cited Corresponding Author Award (general chemistry); ACS / Elsevier Outstanding Reviewer Awards, etc. He is a reviewer of over 50 international journals and expert project reviewer of various national/international funding agencies. He is Associate Editor of Sensors International and an editorial board member of a Materials Science for Energy Technologies by KeAi and Elsevier, World journal of methodology, USA;  Frontiers of Biosciences, USA; Reports in Physical Sciences, Singapore. 

Bibliographic Information

  • Book Title: Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing

  • Editors: Pankaj Suman, Pranjal Chandra

  • DOI: https://doi.org/10.1007/978-981-15-5823-8

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2021

  • Hardcover ISBN: 978-981-15-5822-1Published: 13 October 2020

  • Softcover ISBN: 978-981-15-5825-2Published: 14 October 2021

  • eBook ISBN: 978-981-15-5823-8Published: 12 October 2020

  • Edition Number: 1

  • Number of Pages: VIII, 245

  • Number of Illustrations: 4 b/w illustrations, 60 illustrations in colour

  • Topics: Immunology, Biomedical Engineering/Biotechnology, Medical Biochemistry, Molecular Medicine

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access