Overview
Presents the latest research results in the field
Covers all aspects of GSL-mediated signaling and its regulation
Examines in depth viral protein and bacterial toxin protein interactions with host cell GSLs
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Table of contents (6 chapters)
Keywords
About this book
This book presents the latest knowledge and the most recent research results on glycosphingolipid (GSL)-mediated signaling. GSLs are important constituents of the plasma membrane that exert their distinct functions through binding to certain functional proteins. They play a role in various human diseases and also function as human alloantigens. Cellular GSLs are associated with many biological functions such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell–cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein–carbohydrate or carbohydrate–carbohydrate interactions. This book opens by providing the key background on GSL glycan–receptor interactions and mammalian GSL synthesis. Up-to-date information is then presented on all aspects of GSL-dependent signaling. Viral protein and bacterial toxin protein interactions with host cell GSLs are examined in depth, and the concluding chapter is devoted to signaling regulation. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.
Authors and Affiliations
About the author
Prof. Cheorl-Ho Kim
Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, Sungkyunkwan University
Bibliographic Information
Book Title: Glycosphingolipids Signaling
Authors: Cheorl-Ho Kim
DOI: https://doi.org/10.1007/978-981-15-5807-8
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2020
Hardcover ISBN: 978-981-15-5806-1Published: 24 January 2021
Softcover ISBN: 978-981-15-5809-2Published: 25 January 2022
eBook ISBN: 978-981-15-5807-8Published: 23 January 2021
Edition Number: 1
Number of Pages: XVII, 181
Number of Illustrations: 5 b/w illustrations, 25 illustrations in colour
Topics: Gene Expression, Cancer Research, Genetics and Genomics, Biochemistry, general, Membrane Biology