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Hepatitis B Virus Infection

Molecular Virology to Antiviral Drugs

Editors:

  • Reviews key aspects of HBV
  • Covers the clinical management of hepatitis B
  • Discusses the directions of future research

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1179)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-vii
  2. Hepatitis B Virus Infection: Overview

    • Hong Li, Libo Yan, Ying Shi, Duoduo Lv, Jin Shang, Lang Bai et al.
    Pages 1-16
  3. HBV Genome and Life Cycle

    • Jie Wang, Hongxin Huang, Yongzhen Liu, Ran Chen, Ying Yan, Shu Shi et al.
    Pages 17-37
  4. The Regulation of HBV Transcription and Replication

    • Claudia E. Oropeza, Grant Tarnow, Abhayavarshini Sridhar, Taha Y. Taha, Rasha E. Shalaby, Alan McLachlan
    Pages 39-69
  5. Immunopathogenesis of HBV Infection

    • Jun Wu, Meihong Han, Jia Li, Xiaoli Yang, Dongliang Yang
    Pages 71-107
  6. Cell Culture Models and Animal Models for HBV Study

    • Feng Li, Zhuo Wang, Fengyu Hu, Lishan Su
    Pages 109-135
  7. Present and Future Therapies for Chronic Hepatitis B

    • Yachao Tao, Dongbo Wu, Lingyun Zhou, Enqiang Chen, Changhai Liu, Xiaoqiong Tang et al.
    Pages 137-186

About this book

This volume provides a state-of-the-art review of the key aspects of HBV. It covers our current understanding of the HBV genome and lifecycle, liver-enriched factors in the regulation of HBV transcription and translation, HBV protein structures and biological functions, and the immunology and pathogenesis of HBV. It also provides an update on cell and animal models, as well as molecular approaches. 

The respective chapters also cover the clinical management of hepatitis B and discuss future research directions, in particular, the identification of molecular targets for pharmacological intervention. Given its scope, the book offers a valuable resource for students, researchers, clinicians, and health practitioners in the fields of virology, infectious disease, public health etc.

Dr Hong Tang is a Professor and Director of the Center of Infectious Diseases, West China Hospital of Sichuan University.

Editors and Affiliations

  • Center of Infectious Diseases, Division of Infectious Diseases, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

    Hong Tang

About the editor

Dr Hong Tang, recipient of the China National Natural Science Foundation Award for Distinguished Young Scholars, is a Clinical Professor and Director of the Center of Infectious Diseases, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University. Dr Tang received her MD and PhD from West China University of Medical Sciences, and subsequently completed a postdoctoral fellowship at the Department of Cell Biology, Scripps Research Institute, USA; and a further fellowship at the Department of Molecular Biology, Cancer Research Institute, Kanazawa University, Japan. She currently serves as vice chairperson of the Chinese Society of Infectious Diseases; vice chairperson of the Chinese Physician Association for Infectious Diseases; and chairperson of the Hepatology Society, Sichuan Medical Association (SMA).

As a principal investigator, she has received more than 20 Chinese National grants in the field of infectious diseases focusing on the molecular biology, pathogenic mechanism and clinical management of HBV and HCV infections; she has also been responsible for more than 40 multicentre clinical trials studying the efficacy and safety of anti-HBV and anti-HCV drugs. She has published more than 100 articles and reviews (mainly in the field of viral hepatitis) in international journals including Hepatology, Proc Natl Acad Sci USA and J Virol.

Bibliographic Information

  • Book Title: Hepatitis B Virus Infection

  • Book Subtitle: Molecular Virology to Antiviral Drugs

  • Editors: Hong Tang

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-981-13-9151-4

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2020

  • Hardcover ISBN: 978-981-13-9150-7Published: 27 November 2019

  • Softcover ISBN: 978-981-13-9153-8Published: 27 November 2020

  • eBook ISBN: 978-981-13-9151-4Published: 18 November 2019

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VII, 186

  • Number of Illustrations: 5 b/w illustrations, 14 illustrations in colour

  • Topics: Virology, Infectious Diseases, Public Health

Buy it now

Buying options

eBook USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access