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Engineering of Micro/Nano Biosystems

Fundamentals & Applications

  • Brings together expertise in biology, fluidics, mechanics, optics, electrical engineering, magnetism, micro/nano fabrication and characterization techniques for the design and building of bio-devices and lab-on-chip systems
  • Provides comprehensive information on biological processes and physical phenomena at the micro/nano scale involved in transport, manipulation and bio sensing in highly miniaturized fluidic and/or bio-devices
  • Covers a broad range of techniques used in state-of-the-art micro/nano fluidic and bio devices both from the theoretical and engineering point of view
  • Explains remaining scientific and technical challenges to overcome commercialization bottlenecks and gives general guidelines for the design of state-of-the art micro-nano Biosystems

Part of the book series: Microtechnology and MEMS (MEMS)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-viii
  2. Introduction

    • Alain Bosseboeuf, Kukjin Chun
    Pages 1-6
  3. Basics of Micro/Nano Fluidics and Biology

    • Olivier Français, Morgan Madec, Norbert Dumas, Denis Funfschilling, Wilfried Uhring
    Pages 7-87
  4. Micro/Nano Fabrication and Packaging Technologies for Bio Systems

    • Yeong Eun Yoo, Claire Smadja, Mehdi Ammar
    Pages 89-137
  5. Mechanics for Fluidics and Bio-Devices

    • Luis Guillermo Villanueva, Annalisa De Pastina, Magalie Faivre
    Pages 139-196
  6. Optics and Fluidics

    • Amos Chungwon Lee, Jinhyun Kim, Jinseong Noh, Howon Lee, Sunghoon Kwon
    Pages 197-234
  7. Electricity for Fluidics and Bio-Devices

    • Hyomin Lee, Sung Jae Kim, Marie Frenea-Robin, Bruno Le Pioufle, Thi Hong Nhung Dinh, Stephane Serfaty et al.
    Pages 235-308
  8. Magnetophoresis in Bio-Devices

    • Anne-Laure Deman, Damien Le Roy
    Pages 309-361
  9. Conclusion

    • Alain Bosseboeuf, Kukjin Chun
    Pages 363-366
  10. Back Matter

    Pages 367-368

About this book

This tutorial book offers an in-depth overview of the fundamental principles of micro/nano technologies and devices related to sensing, actuation and diagnosis in fluidics and biosystems. Research in the MEMS/NEMS and lab-on-chip fields has seen rapid growth in both academic and industrial domains, as these biodevices and systems are increasingly replacing traditional large size diagnostic tools. This book is unique in describing not only the devices and technologies but also the basic principles of their operation.


The comprehensive description of the fabrication, packaging and principles of micro/nano biosystems presented in this book offers guidance for researchers designing and implementing these biosystems across diverse fields including medical, pharmaceutical and biological sciences. The book provides a detailed overview of the fundamental mechanical, optical, electrical and magnetic principles involved, together with the technologies required for the design, fabrication and characterization of micro/nano fluidic systems and bio-devices.


Written by a collaborative team from France and Korea, the book is suitable for academics, researchers, advanced level students and industrial manufacturers.


Editors and Affiliations

  • Faculty of Engineering, EPF-Ecole d’Ingénieurs, Sceaux, France

    Gregory Barbillon

  • Centre de Nanosciences et de Nanotechnologies (C2N) CNRS, University of Paris-Sud, University of Paris-Saclay, Orsay, France

    Alain Bosseboeuf

  • Seoul National University, Seoul, Korea (Republic of)

    Kukjin Chun

  • Institut des Nanotechnologies de Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France

    Rosaria Ferrigno

  • ESYCOM Laboratory, ESIEE Paris, Noisy-Le-Grand, France

    Olivier Français

About the editors

Dr. HDR. Grégory Barbillon completed his PhD in Physics (2007) with greatest distinction at the University of Technology of Troyes (France). Then, he obtained his Habilitation (HDR) in Physics (2013) at the University of Paris Sud (Orsay, France). From September 2017, he is Professor of Physics at the Faculty of Engineering "EPF - Ecole d'Ingénieurs" (Sceaux, France). His research interests are focused on Plasmonics, Nano-Optics, Non-Linear Optics, Nanophotonics, Condensed Matter Physics, Optical Sensing, Biosensing, Nanotechnology, Surface Enhanced Spectroscopies, Sum Frequency Generation Spectroscopy, Materials Chemistry, Physical Chemistry, Fluorescence.

Dr. Alain Bosseboeuf received in 1980 a master degree in microelectronics from INPG and a telecommunication engineer diploma from ENSTBr and in 1981 a master degree in Solid State Physics from University Paris 6. He received in 1989 the state PhD degree in Physics from University Paris Sud (Orsay). Since1983 he works as a CNRS full-time researcher first in Institut d’Electronique Fondamentale (IEF) and since june 2016 in Centre for Nanoscience and nanotechnology (C2N) a joint research institute of CNRS and University Paris-Sud. He worked for 10 years on thin film deposition and characterization and then in the field of micro/nanosystems. He led for 10 years the research group “NanoBio and Micro/nanosystems” of IEF. He belonged to various expert, steering and conference committees in the field of microsystems. Since November 2005, he is coordinating the international research network NAMIS (Nano and Microsystems) involving 12 partners from 10 countries and 3 continents. His current interests include thin films, MEMS and packaging technologies, and the development of associated characterisation tools.

Prof. Kukjin Chun received the B.S.degree in Electronics Engineering from Seoul National University in 1977 and the M.S. and Ph.D. degrees in Electrical Engineering from the University of Michigan in 1981 and 1986, respectively. He was an Assistant Professor in the Department of Electrical and Computer Engineering at Washington State University from 1986 to 1989. He joined the faculty of Seoul National University in 1989, where he is currently a Professor in the School of Electrical Engineering. He is a senior member of IEEE and a life member of IEEK. He has been a director of the Center for Advanced Transceiver System since 2000, which develops RF front-end solution for next-generation wireless communication systems. His research interests include integrated sensors, intelligent microsystems, and MEMS processing technologies.

Prof. Rosaria Ferrigno received her PhD in Electrochemistry (1998) from the Swiss Federal Institute of Lausanne. She joined the faculty of University of Lyon in 2003, where she is currently Professor in the Electrical Engineering Department. Her research interests include Lab-on-a-Chip, Point-of-Care devices and microfluidics science with the main target to develop new in-vitro diagnostic devices. 

Prof. Français Olivier received his PhD in applied physics (1998) from ENS- Cachan (France). He joined ESIEE-Paris (Marne la Vallée, France) from 1998 to 2004 to work on MEMS devices. In 2004, he had been recruited as an Assistant Professor at CNAM (Paris, France) and achieved projects on resonant sensors and microfluidics. In 2009, he joined ENS-Cachan to develop research and teaching around Microfluidics and BioMEMS. He focused his activity around cell biochips and biomimetic devices. He became specialised on study of interaction between electric fields and biological cells. In 2016, he got a full professor position at ESIEE-Paris engineering school in the biotechnology department. He is in charge for the development of microfluidics and its application towards biological applications.

Bibliographic Information

Buy it now

Buying options

eBook USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access