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Biochemical and Biophysical Roles of Cell Surface Molecules

  • Book
  • © 2018

Overview

  • Provides comprehensive updates on the major advances in the field of membrane biology research
  • Explains concepts in a lucid manner, using actual in-depth laboratory data on cell-surface molecules
  • Covers topics ranging from the role of cell surface receptors in neurobiology to infectious diseases

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1112)

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Table of contents (24 chapters)

  1. Membrane Organization

  2. Biophysics of Membrane Proteins and Cell Surface Macromolecules

  3. G-Protein Coupled Receptors: From Structure to Function

  4. Cell Surface Macromolecules in Neurobiology

  5. Cell Surface Macromolecules: Infection, Immunity and Disease

Keywords

About this book

Cell surface small molecules and macromolecules, such as members of cholesterol family (including steroid hormones), the glycolipid family (sphingolipids), the glycoprotein family (both N-linked and O-linked), and a vast array of other receptors have been shown to be involved in normal and abnormal cellular processes. The 11th International Symposium on Cell Surface Macromolecules, held in Mohali, India, in February 2017 provided a comprehensive update on the major advances in this area.

Presenting selected contributions from this meeting, this book comprises 24 chapters, which provide in-depth analyses of data on the role of cell surface macromolecules in cellular function and their alterations associated with pathological conditions. It includes comprehensive research papers and critical overviews of the functional role of cell surface molecules, discussing topics such as biochemical, biophysical, and cell biological approaches to study cell membrane molecules, and metabolism of glycoconjugates.

Editors and Affiliations

  • Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Mohali, India

    Kausik Chattopadhyay

  • Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, USA

    Subhash C. Basu

About the editors

Dr. Kausik Chattopadhyay is an Associate Professor in the Department of Biological Sciences at the Indian Institute of Science Education and Research Mohali (IISER Mohali). He received his PhD degree in Biochemistry from the Calcutta University in 2004, and subsequently completed his post-doctoral research with Prof. Stanley G. Nathenson at the Department of Microbiology and Immunology at the Albert Einstein College of Medicine, Bronx, New York, USA. He joined IISER Mohali as an Assistant Professor in 2009, and became Associate Professor in 2014. His research interests focus on understanding the structure-function mechanisms of membrane-damaging, bacterial, pore-forming toxins, and their implications for the host-pathogen interaction processes and immunity. He received the prestigious National BioScience Award for Career Development for the year 2014, awarded by the Department of Biotechnology, Ministry of Science & Technology, Government of India for his work in this area.

 

Dr. Subhash C. Basu is an Emeritus Professor at the University of Notre Dame (UND), Department of Chemistry and Biochemistry and also the president of the CDDRF (Cancer Drug Delivery Research Foundation). He received his PhD degree in Biochemistry in 1966 from the University of Michigan and was a Helen Hay Whitney Research Fellow (1966-70) under Professor Saul Roseman at the Johns Hopkins University. He joined both the teaching and research faculty at the UND in 1970 and became a Full Professor and Chairman of the Biochemistry, Biophysics and Molecular Biology program in 1983. He was awarded a D.Sc. degree in Biochemistry from the University of Calcutta, India in 1976 . He received the Jacob Javits Neuroscience Research Award from NIH (1989-98), and the S. C. Roy Medal of Achievement Award   from the University of Calcutta, India in 1990. He was elected to the prestigious Johns Hopkins Honor Society in 1995. He has been an elected fellowof the American Association for the Advancement of Sciences (FAAAS) since 1988. He received the “NRI-2015 Award” Trophy in the International Professional category from the respected India Times newspaper in April 2015.


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