Overview
- Introduces mechanisms and methodologies of chromosome translocations
- Provides a clear overview of the basics
- Reviews up-to-date knowledge of chromosome translocations
- Contributions from experts in the field
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1044)
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Table of contents (10 chapters)
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Front Matter
Keywords
About this book
This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases.
The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation.
It is a valuable resource for students and researchers alike, providing insights into chromosome translocations and, potentially, other genomic aberrations involved in understanding and curing human diseases.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Chromosome Translocation
Editors: Yu Zhang
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-981-13-0593-1
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2018
Hardcover ISBN: 978-981-13-0592-4Published: 18 July 2018
Softcover ISBN: 978-981-13-4459-6Published: 29 December 2018
eBook ISBN: 978-981-13-0593-1Published: 28 June 2018
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: V, 168
Number of Illustrations: 2 b/w illustrations, 27 illustrations in colour
Topics: Human Genetics, Cell Biology