ICSA Book Series in Statistics

Biopharmaceutical Applied Statistics Symposium

Volume 2 Biostatistical Analysis of Clinical Trials

Editors: Peace, Karl E., Chen, Ding-Geng, Menon, Sandeep (Eds.)

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  • Discusses updated design and analysis methods for biopharmaceutical clinical trialsIncludes chapters written by internationally respected authors from academia, government and industry who possess substantial hands-on experience designing and analyzing biopharmaceutical clinical trials
  • Provides illustrative examples of the design and analysis of biopharmaceutical clinical trials
  • Provides computer programs to facilitate the understanding and applications
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eBook 79,72 €
price for Spain (gross)
  • ISBN 978-981-10-7826-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 103,99 €
price for Spain (gross)
  • ISBN 978-981-10-7825-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

This BASS book Series publishes selected high-quality papers reflecting recent advances in the design and biostatistical analysis of biopharmaceutical experiments – particularly biopharmaceutical clinical trials.  The papers were selected from invited presentations at the Biopharmaceutical Applied Statistics Symposium (BASS), which was founded by the first Editor in 1994 and has since become the premier international conference in biopharmaceutical statistics. The primary aims of the BASS are: 1) to raise funding to support graduate students in biostatistics programs, and 2) to provide an opportunity for professionals engaged in pharmaceutical drug research and development to share insights into solving the problems they encounter.
The BASS book series is initially divided into three volumes addressing: 1) Design of Clinical Trials; 2) Biostatistical Analysis of Clinical Trials; and 3) Pharmaceutical Applications.  
This book is the second of the 3-volume book series. The topics covered include: Statistical Approaches to the Meta-analysis of Randomized Clinical Trials, Collaborative Targeted Maximum Likelihood Estimation to Assess Causal Effects in Observational Studies, Generalized Tests in Clinical Trials, Discrete Time-to-event and Score-based Methods with Application to Composite Endpoint for Assessing Evidence of Disease Activity-Free , Imputing Missing Data Using a Surrogate Biomarker: Analyzing the Incidence of Endometrial Hyperplasia, Selected Statistical Issues in Patient-reported Outcomes, Network Meta-analysis, Detecting Safety Signals Among Adverse Events in Clinical Trials, Applied Meta-analysis Using R, Treatment of Missing Data in Comparative Effectiveness Research, Causal Estimands: A Common Language for Missing Data, Bayesian Subgroup Analysis with Examples, Statistical Methods in Diagnostic Devices, A Question-Based Approach to the Analysis of Safety Data, Analysis of Two-stage Adaptive Seamless Trial Design, and Multiplicity Problems in Clinical Trials – A Regulatory Perspective.

Table of contents (12 chapters)

Table of contents (12 chapters)
  • Collaborative Targeted Maximum Likelihood Estimation to Assess Causal Effects in Observational Studies

    Gruber, Susan (et al.)

    Pages 1-23

  • Generalized Tests in Clinical Trials

    Ogenstad, Stephan

    Pages 25-42

  • Discrete Time-to-Event and Rank-Based Methods with Application to Composite Endpoint for Assessing Evidence of Disease Activity

    Okwuokenye, Macaulay

    Pages 43-56

  • Imputing Missing Data Using a Surrogate Biomarker: Analyzing the Incidence of Endometrial Hyperplasia

    Lim, P. (et al.)

    Pages 57-67

  • Advancing Interpretation of Patient-Reported Outcomes

    Cappelleri, Joseph C. (et al.)

    Pages 69-89

Buy this book

eBook 79,72 €
price for Spain (gross)
  • ISBN 978-981-10-7826-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 103,99 €
price for Spain (gross)
  • ISBN 978-981-10-7825-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Biopharmaceutical Applied Statistics Symposium
Book Subtitle
Volume 2 Biostatistical Analysis of Clinical Trials
Editors
  • Karl E. Peace
  • Ding-Geng Chen
  • Sandeep Menon
Series Title
ICSA Book Series in Statistics
Copyright
2018
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-10-7826-2
DOI
10.1007/978-981-10-7826-2
Hardcover ISBN
978-981-10-7825-5
Series ISSN
2199-0980
Edition Number
1
Number of Pages
XIII, 245
Number of Illustrations
16 b/w illustrations, 18 illustrations in colour
Topics