Stress Response Pathways in Cancer

From Molecular Targets to Novel Therapeutics

Editors: Wondrak, Georg (Ed.)

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  • The book covers very recent research that promises to revolutionize cancer-directed chemotherapeutic interventions
  • The book provides a unique translational coverage between molecular cancer biology and cancer-directed therapeutic development
  • The book provides state-of-the-art coverage written by recognized experts from five continents
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eBook 117,69 €
price for Spain (gross)
  • ISBN 978-94-017-9421-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 166,39 €
price for Spain (gross)
  • ISBN 978-94-017-9420-6
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 145,78 €
price for Spain (gross)
  • ISBN 978-94-024-0385-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit cancer patients in the near future. Coauthored by recognized leaders in cancer research from five continents, this novel book provides a comprehensive perspective on cell stress response pathways and therapeutic opportunities. Focusing on the role of genotoxic, proteotoxic, oxidative, metabolic, and inflammatory stress in tumorigenesis, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in cancer and therapeutic development.

Table of contents (18 chapters)

Table of contents (18 chapters)
  • Introduction to Cell Stress Responses in Cancer: The Big Picture

    Pages 1-5

    Wondrak, Georg T.

  • DNA Repair Dysregulation in Cancer: From Molecular Mechanisms to Synthetic Lethal Opportunities

    Pages 7-28

    Nickoloff, Jac A.

  • Cell Cycle Checkpoint and DNA Damage Response Defects as Anticancer Targets: From Molecular Mechanisms to Therapeutic Opportunities

    Pages 29-49

    Spoerri, Loredana (et al.)

  • p53 at the Crossroads Between Stress Response Signaling and Tumorigenesis: From Molecular Mechanisms to Therapeutic Opportunities

    Pages 51-73

    Giono, Luciana E. (et al.)

  • Sirtuins as a Double-Edged Sword in Cancer: From Molecular Mechanisms to Therapeutic Opportunities

    Pages 75-106

    Sima, Núria (et al.)

Buy this book

eBook 117,69 €
price for Spain (gross)
  • ISBN 978-94-017-9421-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 166,39 €
price for Spain (gross)
  • ISBN 978-94-017-9420-6
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 145,78 €
price for Spain (gross)
  • ISBN 978-94-024-0385-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Stress Response Pathways in Cancer
Book Subtitle
From Molecular Targets to Novel Therapeutics
Editors
  • Georg Wondrak
Copyright
2015
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-017-9421-3
DOI
10.1007/978-94-017-9421-3
Hardcover ISBN
978-94-017-9420-6
Softcover ISBN
978-94-024-0385-5
Edition Number
1
Number of Pages
XII, 446
Number of Illustrations
4 b/w illustrations, 52 illustrations in colour
Topics