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Intracellular Delivery II

Fundamentals and Applications

  • Book
  • © 2014

Overview

Editors:
  1. Aleš Prokop

    1. Chemical and Biological Engineering, Vanderbilt University, Nashville, USA

  2. Yasuhiko Iwasaki

    1. Chemistry and Materials Engineering, Kansai University, Osaka, Japan

  3. Atsushi Harada

    1. Department of Applied Chemistry, Osaka Prefecture University, Osaka, Japan

  • Some chapters will serve as tutorials as they will feature step-by-step nanocarrier preparation and function
  • A new section on nanocarrier assembly via computing will provide a vehicle for future direction, that is towards their rational design
  • Applications in the wound healing is particularly emphasized
  • Includes supplementary material: sn.pub/extras

Part of the book series: Fundamental Biomedical Technologies (FBMT, volume 7)

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  • 16 Citations

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About this book

This volume is a continuation of Volume 1 following the previously published Editorial. More emphasis is given to novel nanocarrier designs, their characterization and function, and applications for drug discovery and treatment. A number of chapters will deal with nanofibers as a new major application within the biomedical field with a very high success rate particularly in wound healing and diabetic foot and spine injuries. A major new subdivision will deal with mathematical methods for the assembly of nanocarriers both for simulation and function.

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xix
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  2. Novel Nanocarrier Design and Processing

    1. Front Matter

      Pages 1-1
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    2. Proprietary Nanofiber Technologies and Scale-Up

      • Stanislav Petrík
      Pages 3-16

    3. Magnetically Responsive (Nano)Biocomposites

      • Ivo Šafařík, Kristýna Pospíšková, Kateřina Horská, Zdeňka Maděrová, Mirka Šafaříková
      Pages 17-34

    4. Zwitterionic Nanocarriers for Gene Delivery

      • Yu-Ju Shih, Ching-Wei Tsai, Lemmuel L. Tayo, Yung Chang
      Pages 35-53

    5. Stimuli-Responsive Polymeric Nanocarriers as Promising Drug and Gene Delivery Systems

      • Gurusamy Saravanakumar, Won Jong Kim
      Pages 55-91

    6. Photo-Responsive Polymeric Nanocarriers for On-Demand Drug Delivery

      • Jian Ji, Qiao Jin
      Pages 93-113

  3. Nanocarrier Characterization and Function

    1. Front Matter

      Pages 115-115
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    2. Uptake and Intracellular Trafficking of Nanocarriers

      • Helene Andersen, Ladan Parhamifar, S. Moein Moghimi
      Pages 117-138

    3. Mucus as Physiological Barrier to Intracellular Delivery

      • Eleonore Fröhlich, Eva Roblegg
      Pages 139-163

    4. Investigation of Nanoparticles in Biological Objects by Electron Microscopy Techniques

      • Gabriela Kratošová, Kateřina Dědková, Ivo Vávra, Fedor Čiampor
      Pages 165-187

    5. Gold Nanoparticles for High Resolution Imaging in Modern Immunocytochemistry

      • Adam Schröfel, Dušan Cmarko, Eva Bártová, Ivan Raška
      Pages 189-206

    6. Design of Functional Polymers for Intracellular Nucleic Acids Delivery

      • Hiroyasu Takemoto, Nobuhiro Nishiyama
      Pages 207-217

    7. Membrane-Domain-Selective Drug Targeting Based on Lipid Modification

      • Takeshi Mori, Yoshiki Katayama
      Pages 219-229

    8. Multifunctional Protein-Based Nanoparticles for Cancer Theranosis

      • Luca Vannucci, Elisabetta Falvo, Pierpaolo Ceci
      Pages 231-253

    9. Cytocompatible Phospholipid Polymers for Non-invasive Nanodevices

      • Tomohiro Konno
      Pages 255-264

    10. Intracellular Protein Delivery Using Self-Assembled Amphiphilic Polysaccharide Nanogels

      • Asako Shimoda, Shin-ichi Sawada, Kazunari Akiyoshi
      Pages 265-274

  4. Simulation for Delivery and Function

    1. Front Matter

      Pages 275-275
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    2. Molecular Dynamics Simulations of Polyplexes and Lipoplexes Employed in Gene Delivery

      • Deniz Meneksedag-Erol, Chongbo Sun, Tian Tang, Hasan Uludag
      Pages 277-311

    3. Computational Studies of Highly PEG-ylated Sterically Stabilized Micelles: Self-Assembly and Drug Solubilization

      • Petr Král, Lela Vuković
      Pages 313-326
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Editors and Affiliations

  • Chemical and Biological Engineering, Vanderbilt University, Nashville, USA

    Aleš Prokop

  • Chemistry and Materials Engineering, Kansai University, Osaka, Japan

    Yasuhiko Iwasaki

  • Department of Applied Chemistry, Osaka Prefecture University, Osaka, Japan

    Atsushi Harada

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