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Side-Effects of Anti-Inflammatory Drugs

Part Two Studies in Major Organ Systems

  • Book
  • © 1987

Overview

Editors:
  1. K. D. Rainsford

    1. Department of Pharmacology, University of Cambridge, and Strangeways Research Laboratory, Cambridge, UK

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  2. G. P. Velo

    1. Institute of Pharmacology, University of Verona, Verona, Italy

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Inflammation and Drug Therapy Series (IDTH, volume 2)

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Table of contents (50 chapters)

  1. Front Matter

    Pages i-xxv
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  2. Gastrointestinal Tract (Experimental Aspects)

    1. Front Matter

      Pages 1-1
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    2. Mechanisms of gastric contrasted with intestinal damage by non-steroidal anti-inflammatory drugs

      • K. D. Rainsford
      Pages 3-28

    3. The enterohepatic circulation of some anti-inflammatory drugs may cause intestinal ulcerations

      • K. Brune, B. Nürnberg, I. Szelenyi, H. Vergin
      Pages 29-39

    4. Limitations of laboratory models in predicting gastrointestinal toleration of oxicams and other anti-inflammatory drugs

      • E. H. Wiseman, Y. Noguchi
      Pages 41-54

    5. Why are non-steroidal anti-inflammatory drugs so gastrotoxic, even when given orally as solubilized salt formulations or parenterally?

      • M. W. Whitehouse, K. D. Rainsford
      Pages 55-65

    6. Early and late phases in the formation by anti-inflammatory drugs of intestinal lesions in rats

      • P. Del Soldato, D. Foschi, G. Benoni, G. P. Velo
      Pages 67-81

    7. Role of intestinal microflora in maintaining indomethacin-induced intestinal lesions in rats

      • G. Benoni, P. Del Soldato, L. Cuzzolin, G. P. Velo
      Pages 83-87

    8. Comparison of gastric mucosal damage and prostaglandin formation in arthritis patients treated with carprofen and ibuprofen

      • S. J. Konturek, J. Oleksy, E. Zielonka
      Pages 89-96

    9. Inhibition of prostanoid synthesis by anti-inflammatory drugs in human gastric mucosa

      • P. O. Collins, I. A. Tavares, A. Bennett
      Pages 97-100

    10. Leukotriene formation in the gastrointestinal tract and effects of anti-inflammatory drugs

      • K. W. Dreyling, U. Hoppe, A. Kleine, W. Kozuschek, B. M. Peskar
      Pages 101-112

    11. Evidence for sulphydryl-sensitive process in the mechanisms of acute gastric mucosal injury and defence

      • E. Ezer
      Pages 113-121

    12. Experimental and clinical studies on the prevention of aspirin-induced gastric damage by “cytoprotective” drugs

      • S. J. Konturek, N. Kwiecien, T. Radecki, J. Oleksy
      Pages 123-132

    13. Both E Prostaglandins and prolonged indomethacin treatment exert trophic effects on the gastric mucosa

      • F. Halter, A. Baumgartner, L. Varga, H. R. Koelz
      Pages 133-142

    14. Gastrointestinal side-effects of prostaglandins

      • E. J. S. Boyd, K. G. Wormsley
      Pages 143-149

    15. Investigation of auranofin-induced diarrhoea

      • R. Behrens, M. Deveraux, B. Hazleman, K. Szaz, J. Calvin, G. Neale
      Pages 151-158

    16. Pyrido-pyrimidines — with analgesic and anti-inflammatory activity — inhibit the gastrointestinal mucosal damage induced by different prostaglandin synthesis inhibitors

      • K. Gyires, J. Knoll
      Pages 159-160

    17. Al(OH)3 inhibits aspirin-induced gastric lesions in cats with Heidenhain pouch

      • H. Beck, H. Engler, I. Szelenyi
      Pages 161-162

    18. Polyene phosphatidylcholine: an inhibitor of NSAID gastric toxicity which increases impaired mucosal PGE2 synthesis

      • S. Leyck, A. M. Huther, M. J. Parnham
      Pages 163-164

    19. Prostaglandins prevent red streaks in rat gastric mucosa caused by intravenous aspirin but not by salicylate

      • P. H. Rowe
      Pages 165-166
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Keywords

Editors and Affiliations

  • Department of Pharmacology, University of Cambridge, and Strangeways Research Laboratory, Cambridge, UK

    K. D. Rainsford

  • Institute of Pharmacology, University of Verona, Verona, Italy

    G. P. Velo

Bibliographic Information

  • Book Title: Side-Effects of Anti-Inflammatory Drugs

  • Book Subtitle: Part Two Studies in Major Organ Systems

  • Editors: K. D. Rainsford, G. P. Velo

  • Series Title: Inflammation and Drug Therapy Series

  • DOI: https://doi.org/10.1007/978-94-010-9775-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1987

  • Softcover ISBN: 978-94-010-9777-2Published: 08 May 2012

  • eBook ISBN: 978-94-010-9775-8Published: 06 December 2012

  • Series ISSN: 0923-9405

  • Edition Number: 1

  • Number of Pages: XXVI, 496

  • Number of Illustrations: 8 b/w illustrations

  • Topics: Pharmacology/Toxicology, Rheumatology

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