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Proteins of the Nucleolus

Regulation, Translocation, & Biomedical Functions

  • Book
  • © 2013

Overview

Editors:
  1. Danton H O'Day

    1. , Biology, University of Toronto at Mississauga, Mississauga, Canada

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    You can also search for this editor in PubMed   Google Scholar

  2. Andrew Catalano

    1. , Biology, University of Toronto at Mississauga, Mississauga, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • A comprehensive overview of the diversity of nucleolar function
  • Data presented comes from a wide spectrum of species
  • Leading edge studies presented shed new light on nucleolar processes
  • Biomedical aspects of nucleolar function are detailed

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-vi
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. Proteins of the Nucleolus: An Introduction

      • Danton H. O’Day, Andrew Catalano
      Pages 3-15

  3. The Nucleolus and Nucleolar Proteins

    1. Front Matter

      Pages 17-17
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    2. Functional Consequences of Nuclear and Nucleolar Architecture

      • Eva Bártová, Lenka Stixová
      Pages 19-38

    3. rDNA and Nucleologenesis in Drosophila

      • Patrick DiMario, Allison James, Himanshu Raje
      Pages 39-78

    4. The Nucleolus of Dictyostelium and Other Lower Eukaryotes

      • Andrew Catalano, Danton H. O’Day
      Pages 79-94

    5. Human rDNA Genes: Identification of Four Fractions, Their Functions and Nucleolar Location

      • Nataliya A. Lyapunova, Nataliya N. Veiko, Lev N. Porokhovnik
      Pages 95-118

    6. Chromatin Organization and the Mammalian Nucleolus

      • Attila Németh, Gernot Längst
      Pages 119-148

    7. Chaperones and Multitasking Proteins in the Nucleolus

      • Mohamed Kodiha, Ursula Stochaj
      Pages 149-172

  4. Nucleolar Protein Translocation

    1. Front Matter

      Pages 173-173
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    2. Nucleolar Localization/Retention Signals

      • Eugene V. Sheval, Yana R. Musinova
      Pages 175-196

    3. Nucleolar Transport of Putative GTPase GNL1 and Related Proteins

      • S. Mahalingam, M. R. K. Subba Rao, Neelima Boddapati, T. Indu Jose, Debduti Datta
      Pages 197-207

    4. Nucleolar Protein Anchoring and Translocation

      • Krzysztof StaroÅ„, Agnieszka Girstun
      Pages 209-247

  5. Nucleolar Proteins and Disease

    1. Front Matter

      Pages 249-249
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    2. The Nucleolus as a Stress Response Organelle

      • Mikael S. Lindström, Leena Latonen
      Pages 251-273

    3. The Nucleolar Aspect of Breast Cancer

      • Judy Yan, Damu Tang
      Pages 275-304

    4. Cysteine Proteinase Inhibitors in the Nucleus and Nucleolus in Activated Macrophages

      • NataÅ¡a Kopitar-Jerala
      Pages 305-321

    5. Nucleolar Proteins and Cancer: The Roles of Aurora A-Interacting Nucleolar Proteins in Mitosis and Cancer

      • Jyoti Iyer, Saili Moghe, Manabu Furukawa, Ming-Ying Tsai
      Pages 323-342

    6. Nucleolar Transplantation and Human Embryogenesis

      • Helena Fulka, Alena Langerova, Stanislava Martinkova, Josef Fulka Jr.
      Pages 343-357
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Keywords

About this book

This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer. This book also brings together work from several different species, from human to Drosophila to Dictyostelium and other eukaryotic microbes. The final chapter summarizes some of the issues brought up in the various chapters with a view to future research. This book supports the continued emergence of the nucleolus as a dynamic intranuclear region that oversees a vast diversity of events.

Editors and Affiliations

  • , Biology, University of Toronto at Mississauga, Mississauga, Canada

    Danton H O'Day, Andrew Catalano

Bibliographic Information

  • Book Title: Proteins of the Nucleolus

  • Book Subtitle: Regulation, Translocation, & Biomedical Functions

  • Editors: Danton H O'Day, Andrew Catalano

  • DOI: https://doi.org/10.1007/978-94-007-5818-6

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2013

  • Hardcover ISBN: 978-94-007-5817-9Published: 09 March 2013

  • Softcover ISBN: 978-94-007-9718-5Published: 12 April 2015

  • eBook ISBN: 978-94-007-5818-6Published: 26 February 2013

  • Edition Number: 1

  • Number of Pages: VI, 371

  • Topics: Protein Science, Cancer Research, Biomedicine general, Biological Microscopy

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