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  • © 2013

Oxidative Stress and Redox Regulation

  • The first time that experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology have come together to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease
  • A complete overview of oxidative stress biology written by the leading researches in the field
  • Outlines the role of oxidative stress and its function as an important signaling tool for setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-x
  2. The Chemistry of Thiol Oxidation and Detection

    • Mauro Lo Conte, Kate S. Carroll
    Pages 1-42
  3. Redox Homeostasis

    • Joris Messens, Nicolas Rouhier, Jean-François Collet
    Pages 59-84
  4. Sulfenic Acids and Peroxiredoxins in Oxidant Defense and Signaling

    • Leslie B. Poole, Kimberly J. Nelson, P. Andrew Karplus
    Pages 85-118
  5. Fluorescent Imaging of Redox Species in Multicellular Organisms

    • Yuuta Fujikawa, Bruce Morgan, Tobias P. Dick
    Pages 119-155
  6. Redox Proteomics

    • Alexandra Müller, Lars I. Leichert
    Pages 157-186
  7. Computational Redox Biology: Methods and Applications

    • Stefano M. Marino, Goedele Roos, Vadim N. Gladyshev
    Pages 187-211
  8. Redox Regulation in Plants: Glutathione and “Redoxin” Related Families

    • J. P. Jacquot, K. J. Dietz, N. Rouhier, E. Meux, P. A. Lallement, B. Selles et al.
    Pages 213-231
  9. Prokaryotic Redox Switches

    • John D. Helmann
    Pages 233-276
  10. Combating Oxidative/Nitrosative Stress with Electrophilic Counterattack Strategies

    • Takumi Satoh, Mohd Waseem Akhtar, Stuart A. Lipton
    Pages 277-307
  11. Redox Regulation of Stem Cell Function

    • Heinrich Jasper, Dirk Bohmann
    Pages 343-357
  12. Oxidative Stress in Infectious Diseases

    • Esther Jortzik, Katja Becker
    Pages 359-388
  13. Role of Oxidative Stress in Aging

    • D. Knoefler, H. L. Tienson, U. Jakob
    Pages 389-426
  14. Oxidative Stress in Cancer

    • Peter Storz
    Pages 427-447
  15. Redox Pathways as a Platform in Drug Development

    • Danyelle M. Townsend, Kenneth D. Tew
    Pages 449-476
  16. Back Matter

    Pages 477-483

About this book

Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.

Editors and Affiliations

  • Mol.,Cel. and Developmental Biology, University of Michigan, Ann Arbor, USA

    Ursula Jakob

  • The Alexander Silberman Institute of Life Science, Department of Biological Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel

    Dana Reichmann

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access