Tumors of the Central Nervous System, Volume 8
Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma
Editors: Hayat, M.A. (Ed.)
Free Preview- New technologies and their applications in tumor diagnosis, treatment, and prognosis are discussed
- Methods to assess the effectiveness of cancer treatments are presented
- The importance of the quality of life after cancer therapy is pointed out
- Molecular profiling of brain tumors to select targeted therapy in clinical trials is explained
- A large number of color figures are included
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- About this book
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With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the role of E-cadherin gene instability, carbonic anhydrase II, urokinase plasminogen activator, and Wnt signaling in meningioma. Contributors explain the genetic and clinical features associated with recurring meningioma, including the role played by erythropoietin receptor, and examine the way in which OTX2 transcription factor functions as an oncogene in medulloblastoma. With much more besides, including discussion of the molecular mechanisms that result in resistance to chemotherapy in medulloblastoma, this volume and its companions have a positive role to play in inspiring a new generation of researchers to design new drugs that are better targeted—and thus more effective.
- Reviews
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From the reviews:
“This volume in the series, Tumors of the Central Nervous System, explores recent developments in tumor biology and newer classification and treatment information for seven distinct types of brain tumors. … The book is written for oncologists, both fellows and practitioners, neuro-oncologists, neurologists, neuropathologists, and neurosurgeons. … In addition to providing an update, the book can also inspire a new generation of researchers in tumor biology and in the design of more effective and scientifically based chemotherapy.” (Ramsis Farid Ghaly, Doody’s Review Service, October, 2012)
- Table of contents (33 chapters)
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Astrocytoma Cell Line: Role of Brain Natriuretic Peptide
Pages 3-11
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Malignant Brain Astrocytomas: Extent of Resection Affects Survival
Pages 13-20
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Medulloblastoma: Classification (A Review)
Pages 23-33
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Medulloblastomas: Clinically Important MicroRNA Genes
Pages 35-46
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Medulloblastoma: Role of OTX2 Transcription Factors
Pages 47-58
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Table of contents (33 chapters)
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Bibliographic Information
- Bibliographic Information
-
- Book Title
- Tumors of the Central Nervous System, Volume 8
- Book Subtitle
- Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma
- Editors
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- M.A. Hayat
- Series Title
- Tumors of the Central Nervous System
- Series Volume
- 8
- Copyright
- 2012
- Publisher
- Springer Netherlands
- Copyright Holder
- Springer Science+Business Media B.V.
- eBook ISBN
- 978-94-007-4213-0
- DOI
- 10.1007/978-94-007-4213-0
- Hardcover ISBN
- 978-94-007-4212-3
- Softcover ISBN
- 978-94-024-0601-6
- Series ISSN
- 2215-096X
- Edition Number
- 1
- Number of Pages
- XXXVII, 347
- Topics
