Calcium Signaling

1. Front Matter

   Pages i-xiii

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2. The Regulation of a Cell’s Ca2+ Signaling Toolkit: The Ca2+ Homeostasome

   • Beat Schwaller

   Pages 1-25

3. Methods to Detect Ca2+ in Living Cells

   • Joseph D. Bruton, Arthur J. Cheng, Håkan Westerblad

   Pages 27-43

4. Development and Optimization of FLIPR High Throughput Calcium Assays for Ion Channels and GPCRs

   • Irina Vetter

   Pages 45-82

5. Two-Photon Calcium Imaging in the Intact Brain

   • Marco Dal Maschio, Riccardo Beltramo, Angela Michela De Stasi, Tommaso Fellin

   Pages 83-102

6. Signaling Through the Extracellular Calcium-Sensing Receptor (CaSR)

   • Bandana Chakravarti, Naibedya Chattopadhyay, Edward M. Brown

   Pages 103-142

7. Ca2+ Signaling: An Outlook on the Characterization of Ca2+ Channels and Their Importance in Cellular Functions

   • Jordan Karlstad, Yuyang Sun, Brij B. Singh

   Pages 143-157

8. Ryanodine Receptor Calcium Release Channels: An Evolutionary Perspective

   • John J. Mackrill

   Pages 159-182

9. Techniques and Methodologies to Study the Ryanodine Receptor at the Molecular, Subcellular and Cellular Level

   • Cedric Viero, N. Lowri Thomas, Joanne Euden, Sammy A. Mason, Christopher H. George, Alan J. Williams

   Pages 183-215

10. Ryanodine Receptor Physiology and Its Role in Disease

    • Johanna T. Lanner

    Pages 217-234

11. Phospholipase C

    • Charlotte M. Vines

    Pages 235-254

12. Inositol 1,4,5-Trisphosphate and Its Receptors

    • Jan B. Parys, Humbert De Smedt

    Pages 255-279

13. The Discovery and Structural Investigation of the IP3 Receptor and the Associated IRBIT Protein

    • Katsuhiko Mikoshiba

    Pages 281-304

14. Pyridine Nucleotide Metabolites and Calcium Release from Intracellular Stores

    • Antony Galione, Kai-Ting Chuang

    Pages 305-323

15. NAADP on Target

    • Robert Hooper, Sandip Patel

    Pages 325-347

16. Store-Operated Ca2+ Entry

    • Alejandro Berna-Erro, Pedro C. Redondo, Juan A. Rosado

    Pages 349-382

17. Structure, Regulation and Biophysics of ICRAC, STIM/Orai1

    • Isabella Derler, Josef Madl, Gerhard Schütz, Christoph Romanin

    Pages 383-410

18. Mitochondria-Associated Membranes (MAMs) as Hotspot Ca2+ Signaling Units

    • Angela Bononi, Sonia Missiroli, Federica Poletti, Jan M. Suski, Chiara Agnoletto, Massimo Bonora et al.

    Pages 411-437

19. Calcium Around the Golgi Apparatus: Implications for Intracellular Membrane Trafficking

    • Massimo Micaroni

    Pages 439-460

20. Calcium Binding Proteins

    • Matilde Yáñez, José Gil-Longo, Manuel Campos-Toimil

    Pages 461-482

Calcium signaling contains a unique selection of chapters that cover a wide range of contemporary topics in this ubiquitous and diverse system of cell signaling. This book has the flavor of a primary text book, but it is much more than that. It covers topics ranging from the fundamental aspects of calcium signaling to its clinical implications, in a thoughtful and comprehensive way. It discusses cutting edge researches, and critical issues at depth, and it presents many testable hypotheses for future research. It includes the theoretical and the methodological topics as well as topics related to mathematical modeling, and simulations. If you want to read about calcium signaling in different mammalian cells, oocytes, Zebrafishes, and even in plants, in one and the same book, then this book will not disappoint you. From the beginners to the experts in the field of calcium signaling, everybody will find something useful in this very timely book.

• Calcium signaling
• Cell biology
• Cell signaling
• Ion channels
• Signal transduction
• Receptors

• , Department of Clinical Sciences and Educ, Karolinska Institutet, Stockholm, Sweden

  Md. Shahidul Islam

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