Melatonin, Neuroprotective Agents and Antidepressant Therapy
Editors: López-Muñoz, F., Srinivasan, V., de Berardis, D., Álamo, C., Kato, T.A. (Eds.)
Free Preview- Detailed information on etiology of mood disorders
- Provides recent thoughts on melatonin, its receptors and their role in circadian rhythms, and sleep and mood disorders
- Describes therapeutic actions of antidepressants
- Includes melatonergic agonists, their use in insomnia, psychiatric and neurological disorders
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- About this book
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This work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders. Mood disorders such as major depressive disorder (MDD), bipolar disorder (BPD) and seasonal affective disorder (SAD) are the most disabling disorders that are among the most expensive of all medical illnesses. The pathophysiology of mood disorders is very complex and involves many mechanisms like circadian rhythm disruption, sleep abnormalities, melatonin rhythm abnormalities and alterations in melatonin receptor mechanisms, abnormalities in monoaminergic neurotransmitter mechanisms, glutamatergic release mechanisms, hippocampal neurogenesis, and abnormal immune and cytokine release mechanisms. Many antidepressants that are in clinical use today including the recently introduced novel agents like agomelatine or other antidepressants cause clinical remission by resynchronizing disrupted circadian rhythms and melatonin receptor functions, enhancing monoaminergic neurotransmission, promoting hippocampal neurogenesis, and regulating immune mechanisms. This book explains various etiological factors that are involved in the pathogenesis of mood disorders and the mechanisms of therapeutic actions of antidepressants including the recently introduced agomelatine and other antidepressants that exhibit rapid onset of action with greater efficacy and fewer side effects. .
- About the authors
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Prof.Venkataramanujan Srinivasan,Msc, Ph.D MAMS SRI SATHYA SAI MEDICAL EDUCATIONAL AND RESEARCH FOUNDATION An International Medical Sciences Research Study Center “PrasanthiNilayam”, KOVAI, Coimbatore, Tamilnadu, INDIA
- Table of contents (51 chapters)
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History of Pineal Gland as Neuroendocrine Organ and the Discovery of Melatonin
Pages 1-23
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Bibliometric Study of Scientific Research on Melatonin During the Last 25 Years
Pages 25-42
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Neuroimaging of the Pineal Gland: Focus on Primary Insomnia
Pages 43-53
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Melatonin: Basic and Clinical Aspects
Pages 55-64
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Melatonin and Melatonin Receptors in Neuroprotection
Pages 65-75
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Table of contents (51 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Melatonin, Neuroprotective Agents and Antidepressant Therapy
- Editors
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- Francisco López-Muñoz
- Venkataramanujam Srinivasan
- Domenico de Berardis
- Cecilio Álamo
- Takahiro A. Kato
- Copyright
- 2016
- Publisher
- Springer India
- Copyright Holder
- Springer India
- eBook ISBN
- 978-81-322-2803-5
- DOI
- 10.1007/978-81-322-2803-5
- Hardcover ISBN
- 978-81-322-2801-1
- Softcover ISBN
- 978-81-322-3842-3
- Edition Number
- 1
- Number of Pages
- XXV, 921
- Number of Illustrations
- 65 b/w illustrations, 113 illustrations in colour
- Topics
