Editors:
- Presents up-to-date knowledge on Muse cells, newly recognized pluripotent stem cells that will be vital for next-generation medical care
- Covers all aspects from molecular and cellular properties to differentiation ability, tissue repair properties, and the diverse potential clinical applications of Muse cells
- Provides a precise protocol for collection of Muse cells
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1103)
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Table of contents (19 chapters)
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Front Matter
About this book
This book provides the first comprehensive account of multilineage-differentiating stress-enduring (Muse) cells, a pluripotent and non-tumorigenic subpopulation of mesenchymal stem cells (MSCs) that have the ability to detect damage signals, migrate to damaged sites, and spontaneously differentiate into cells compatible with the affected tissue, thereby enabling repair of all tissue types. The coverage encompasses everything from the basic properties of Muse cells to their tissue repair effects and potential clinical applications—for example, in acute myocardial infarction, stroke, skin injuries and ulcers, renal failure, and liver disease. An important technical chapter provides a practical and precise protocol for the isolation of Muse cells, which will enable readers to use Muse cells in their own research. In offering fascinating insights into the strategic organization of the body’s reparative function and explaining how full utilization of Muse cells may significantly enhancethe effectiveness of MSC treatment, the book will be of high value for Ph.D. students, postdocs, basic researchers, clinical doctors, and industrial developers.
Editors and Affiliations
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Tohoku University Graduate School of Medicine, Sendai, Japan
Mari Dezawa
About the editor
Bibliographic Information
Book Title: Muse Cells
Book Subtitle: Endogenous Reparative Pluripotent Stem Cells
Editors: Mari Dezawa
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-4-431-56847-6
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Japan KK, part of Springer Nature 2018
Hardcover ISBN: 978-4-431-56845-2Published: 12 December 2018
eBook ISBN: 978-4-431-56847-6Published: 27 November 2018
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XII, 315
Number of Illustrations: 43 b/w illustrations, 89 illustrations in colour
Topics: Human Physiology, Stem Cells, Regenerative Medicine/Tissue Engineering, Immunology, Biomedical Engineering/Biotechnology, Cell Physiology