Overview
Contains the most recent research results from leading laboratories on aging in East Asia
Discusses aging mechanisms on the basis of a wide variety of topics at the molecular and cellular levels
Includes a special chapter providing a comprehensive historical overview of biological mechanisms of aging
Buy print copy
Tax calculation will be finalised at checkout
Table of contents (23 chapters)
-
Front Matter
-
From Hypotheses to Mechanisms
-
Front Matter
-
-
Human Longevity: Centenarianism and Progeria
-
Front Matter
-
-
Stem Cells, Cultured Neurons, and Lower Animal Models
-
Front Matter
-
-
Metabolism: Factors Affecting Tissue Aging
-
Front Matter
-
-
Aging Brain: Adult Neurogenesis, Synaptic Plasticity, and Brain Volume
-
Front Matter
-
Keywords
About this book
This book brings together the most up-to-date information on recent research results of leading laboratories on aging science in East Asia, particularly in Japan, Korea, and Hong Kong. Starting with a comprehensive overview of various hypotheses on biological mechanisms of aging by Dr. Sataro Goto, each chapter covers broad aspects of the most recent findings in aging-related topics: centenarian studies and genome analysis of progeria, metabolic biochemistry and neurobiology, longevity controls in yeast and nematodes, oxidative stress and calorie restriction, and neurodegeneration mechanisms in Alzheimer’s and Huntington’s diseases, with further potential therapeutic approaches to these age-related neurodegenerative diseases. Also included, in part, is a summary and the outcomes of a scientific discussion forum called the Asian Aging Core for Longevity (AACL) that has been held annually alternating between Japan and Korea during the last decade. This book can serve as a useful resource for finding appropriate collaborators in the areas it covers. The target readership is made up of graduate students and researchers at universities, medical and/or life-science schools, and biomedical and pharmaceutical institutes.
Why does aging exist? How do we age? How is each organism’s lifespan determined? These are fundamental questions in the field. We may be still far from achieving a complete view of aging mechanisms, but this book, Aging Mechanisms, offers an excellent opportunity to become familiar with the most updated progress in the biomedical research of aging in Japan and Korea, the two leading nations for human longevity.
Reviews
“This text discusses the molecular and cellular aspects of the aging process in C elegans and in mammals. … The audience is primarily those interested in the cell biology of cancer and aging. Students in molecular and cell biochemistry would be interested in this reference.” (Joseph J. Grenier, Amazon.com, December, 2015)
Editors and Affiliations
Bibliographic Information
Book Title: Aging Mechanisms
Book Subtitle: Longevity, Metabolism, and Brain Aging
Editors: Nozomu Mori, Inhee Mook-Jung
DOI: https://doi.org/10.1007/978-4-431-55763-0
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Japan 2015
Hardcover ISBN: 978-4-431-55762-3Published: 04 December 2015
Softcover ISBN: 978-4-431-56688-5Published: 21 March 2019
eBook ISBN: 978-4-431-55763-0Published: 26 November 2015
Edition Number: 1
Number of Pages: XIV, 439
Number of Illustrations: 22 b/w illustrations, 63 illustrations in colour
Topics: Neurosciences, Human Physiology, Geriatrics/Gerontology, Cell Biology