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Optogenetics

Light-Sensing Proteins and Their Applications

  • Book
  • © 2015

Overview

Editors:
  1. Hiromu Yawo

    1. Department of Developmental Biology and Neuroscience, Tohoku University Graduate School of Life Sciences, Sendai, Japan

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  2. Hideki Kandori

    1. Department of Frontier Materials, Nagoya Institute of Technology, Nagoya, Japan

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    You can also search for this editor in PubMed   Google Scholar

  3. Amane Koizumi

    1. National Institutes of Natural Sciences, Tokyo, Japan

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    You can also search for this editor in PubMed   Google Scholar

  • Covers all aspects of optogenetics in a single book
  • Presents topics and future perspectives of each field
  • Comprises chapters all written by leading experts

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-ix
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  2. Light-Sensing Proteins

    1. Front Matter

      Pages 1-1
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    2. History and Perspectives of Light-Sensing Proteins

      • Hideki Kandori
      Pages 3-16

    3. Biology of Light-Sensing Proteins in Plants and Microorganisms

      • Mineo Iseki, Tetsuo Takahashi
      Pages 17-29

    4. Structure-Functional Analysis of Channelrhodopsins

      • Hideaki E. Kato, Ryuichiro Ishitani, Osamu Nureki
      Pages 31-45

    5. Photochemistry of Halorhodopsin

      • Takashi Kikukawa, Naoki Kamo, Makoto Demura
      Pages 47-62

    6. Molecular Mechanisms for Ion Transportation of Microbial Rhodopsins Studied by Light-Induced Difference FTIR Spectroscopy

      • Yuji Furutani
      Pages 63-76

    7. Optogenetic Potentials of Diverse Animal Opsins

      • Akihisa Terakita, Takashi Nagata, Tomohiro Sugihara, Mitsumasa Koyanagi
      Pages 77-88

    8. Color Tuning in Retinylidene Proteins

      • Kota Katayama, Sivakumar Sekharan, Yuki Sudo
      Pages 89-107

  3. Optogenetics in Biological Systems

    1. Front Matter

      Pages 109-109
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    2. General Description: Future Prospects of Optogenetics

      • Hiromu Yawo, Ryo Egawa, Shoko Hososhima, Lei Wen
      Pages 111-131

    3. Optogenetic Manipulation and Probing

      • Masamichi Ohkura, Junko Sadakari, Junichi Nakai
      Pages 133-147

    4. Probing Neuronal Activity Using Genetically Encoded Red Fluorescent Calcium Indicators

      • Takuya Sasaki
      Pages 149-158

    5. Optogenetic Sensors for Monitoring Intracellular Chloride

      • Ken Berglund, Lei Wen, George J. Augustine
      Pages 159-183

    6. Optogenetic Imaging of Protein Activity in the Synapse Using 2-Photon Fluorescence Lifetime Imaging Microscopy

      • Hideji Murakoshi, Akihiro C. E. Shibata
      Pages 185-197

    7. Optogenetics in Drosophila

      • Hiroshi Kohsaka, Akinao Nose
      Pages 199-212

    8. Optogenetics in Caenorhabditis elegans

      • Yuki Tsukada, Ikue Mori
      Pages 213-226

    9. Optogenetics Research Using the Mouse as a Model System

      • Kenji F. Tanaka
      Pages 227-237

  4. Optogenetics in Neuroscience

    1. Front Matter

      Pages 239-239
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    2. Neuroscientific Frontline of Optogenetics

      • Akihiro Yamanaka
      Pages 241-248
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Keywords

About this book

The subject of optogenetics is comprehensively covered in this book, including physical, chemical, and biological topics of light-sensing proteins and their application in biological systems, particularly in neuroscience and medicine and the related opto-electronics. Optogenetics is a new technology that combines genetics and optics. It enables one to manipulate or measure the function of identified cells or neurons in a tissue by light with an accuracy in the range of milliseconds, even in a freely moving animal. Optogenetics has already become a powerful tool for revealing the neural mechanisms underlying behavior and analyzing various physiological phenomena. It is also expected to become useful for treating neural dysfunctions such as Parkinson disease and for the development of a brain–machine interface. This book should be read by any scientist or student performing research in any way related to optogenetics. As a milestone publication on optogenetics, this book will serve asa compass for any researcher, from beginners to experts, to explore this uncharted world.

Editors and Affiliations

  • Department of Developmental Biology and Neuroscience, Tohoku University Graduate School of Life Sciences, Sendai, Japan

    Hiromu Yawo

  • Department of Frontier Materials, Nagoya Institute of Technology, Nagoya, Japan

    Hideki Kandori

  • National Institutes of Natural Sciences, Tokyo, Japan

    Amane Koizumi

Bibliographic Information

  • Book Title: Optogenetics

  • Book Subtitle: Light-Sensing Proteins and Their Applications

  • Editors: Hiromu Yawo, Hideki Kandori, Amane Koizumi

  • DOI: https://doi.org/10.1007/978-4-431-55516-2

  • Publisher: Springer Tokyo

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Japan 2015

  • Softcover ISBN: 978-4-431-56197-2Published: 18 October 2016

  • eBook ISBN: 978-4-431-55516-2Published: 05 June 2015

  • Edition Number: 1

  • Number of Pages: IX, 409

  • Number of Illustrations: 31 b/w illustrations, 111 illustrations in colour

  • Topics: Neurosciences, Cell Biology, Protein Science

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