Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement
Drug Manipulation Strategies and Vehicle Effects
Editors: Dragicevic, Nina, Maibach, Howard I. (Eds.)
Free Preview- Describes in detail enhancement methods in the field of dermal/transdermal drug delivery
- Covers both the best known and the most recently developed chemical and physical methods
- Edited by a team of the most experienced scientists in the field
- Invaluable for researchers, pharmaceutical scientists, practitioners, and students
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- About this book
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This truly comprehensive reference, in a mini-series format with five volumes, offers a detailed description of both well-known and recently introduced methods for percutaneous penetration enhancement. The first three volumes are devoted to the broad range of chemical methods used to enhance the skin delivery of drugs, including the vast variety of chemical penetration enhancers, drug and vehicle manipulation strategies, nanocarriers, and many others. The fourth volume discusses the diverse physical methods used in penetration enhancement, such as sonophoresis, iontophoresis, electroporation, microporation, laser ablation, and microneedles. Determination of drug penetration is covered in the final volume, with a focus especially on mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. This edition of Percutaneous Penetration Enhancers will be an invaluable resource for researchers, pharmaceutical scientists, practitioners, and also students.
- About the authors
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Howard I. Maibach is Professor of Dermatology at the University of California, San Francisco. He is a leading authority in the fields of dermatotoxicology and dermatopharmacology, in which he has conducted much original research and written very extensively, with a total of more than 2,500 publications as lead or co-author. Professor Maibach has served on the editorial boards of more than 30 scientific journals and is a member of many professional societies, including the American Academy of Dermatology and the International Commission on Occupational Health. He has also been the recipient of numerous honors, both within the United States and overseas.
Nina Dragićević-Ćurić graduated from the University of Belgrade, Faculty of Pharmacy in 1999 and subsequently obtained an MSc and a PhD (summa cum laude, Dr. rer. nat.) in Pharmaceutical Technology from the University of Belgrade and the Friedrich-Schiller University, Jena, respectively. Dr. Dragićević-Ćurić is an accredited Specialist in Pharmaceutical Technology. From 2007 to 2013 she was responsible for the preparation of compounded drugs in pharmacies of the state pharmaceutical company Apoteka "Beograd" in Belgrade, and in 2013 she was appointed Director of the Production Department in the same company. She has published in a variety of international journals.
- Reviews
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“This book details the fundamental principles of drug design and formulations to penetrate the skin. It is a very detailed book designed for specialists working in this area of drug delivery technology. … is designed for pharmaceutical scientists working in industry and academia, as well as younger researchers exploring the world of drug delivery via this route.” (Patrick J. McDonnell, Doody’s Book Reviews, April, 2016)
- Table of contents (23 chapters)
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Skin Deep: The Basics of Human Skin Structure and Drug Penetration
Pages 3-11
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Epidermal Lipids and the Intercellular Pathway
Pages 13-18
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The Importance of Stratum Corneum Lipid Organization for Proper Barrier Function
Pages 19-38
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Molecular Structure and Function of the Skin Barrier
Pages 39-42
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The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery
Pages 43-53
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Table of contents (23 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement
- Book Subtitle
- Drug Manipulation Strategies and Vehicle Effects
- Editors
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- Nina Dragicevic
- Howard I. Maibach
- Copyright
- 2015
- Publisher
- Springer-Verlag Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- eBook ISBN
- 978-3-662-45013-0
- DOI
- 10.1007/978-3-662-45013-0
- Hardcover ISBN
- 978-3-662-45012-3
- Softcover ISBN
- 978-3-662-51166-4
- Edition Number
- 1
- Number of Pages
- XVI, 341
- Number of Illustrations
- 80 b/w illustrations, 38 illustrations in colour
- Topics
