Skip to main content
SpringerLink
Log in
SpringerLink
Log in

Rheumatoid Arthritis

Recent Research Advances

  • Conference proceedings
  • © 1992

Overview

Editors:
  1. Josef S. Smolen

    1. 2. Medizinische Abteilung Zentrum fü Diagnostik und Therapie rheumatischer Erkrankungen, Krankenhaus der Stadt Wien-Lainz und Ludwig Boltzmann Institut für Rheumatologie und Balneologie, Wien, Austria

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Joachim R. Kalden

    1. Medizinische Klinik III mit Poliklinik und Institut für Klinische Immunologie und Rheumatologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Ravinder N. Maini

    1. Mathilda and Terence Kennedy Institute of Rheumatology, Hammersmith, London, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (25 papers)

  1. Front Matter

    Pages I-XX
    Download chapter PDF

  2. Introduction

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Is Rheumatoid Arthritis a Disappearing Disease?

      • A. J. Silman
      Pages 3-13

  3. Genetics

    1. Front Matter

      Pages 15-15
      Download chapter PDF

    2. Genetic Factors in Rheumatoid Arthritis

      • J. S. S. Lanchbury, L. I. Sakkas, G. S. Panayi
      Pages 17-28

    3. Rheumatoid Arthritis in Southeastern Europe

      • H. M. Moutsopoulos, P. G. Vlachoyiannopoulos
      Pages 29-37

  4. Pathogenesis

    1. Front Matter

      Pages 39-39
      Download chapter PDF

    2. Pathogenesis of Rheumatoid Arthritis: Cellular and Cytokine Interactions

      • M. Feldmann, F. M. Brennan, M. Field, R. N. Maini
      Pages 41-54

    3. Role of Cellular Adhesion in Rheumatoid Synovitis

      • M. Ziff
      Pages 55-70

    4. Endothelial Cells and Dendritic Cells in Rheumatoid Inflammation

      • Ø. Førre, K. Waalen, J. B. Natvig
      Pages 71-90

    5. Cellular and Humoral Immune Response Against Articular Chondrocytes and Proteoglycans in Rheumatoid Arthritis

      • G. R. Burmester, S. Alsalameh, J. Mollenhauer
      Pages 91-111

    6. Role and Regulation of Synovial MHC Class II Antigens in Rheumatoid Arthritis and Related Diseases

      • L. Klareskog
      Pages 112-121

    7. CD5+ B Cells and Double-Negative T Cells in Rheumatoid Arthritis

      • C. Plater-Zyberk, R. N. Maini, F. M. Brennan, M. Feldmann
      Pages 122-136

    8. The Genetics of Rheumatoid Factors (RF): The V-gene Repertoire of RFs in Rheumatoid Arthritis as Analyzed by Hybridoma Clones

      • J. B. Natvig, I. Randen, K. Thompson, Ø. Førre
      Pages 137-149

    9. Neutrophil Polymorphonuclear Cell Function in Rheumatoid Arthritis

      • P. Youinou, A. Lamour, A. Dumay, P. Le Goff
      Pages 150-163

  5. Etiologic Factors — Bacterial Antigens, Autoantigens, Viruses

    1. Front Matter

      Pages 165-165
      Download chapter PDF

    2. Heat-Shock Proteins and Mycobacterial Antigens

      • W. van Eden, C. J. P. Boog, E. J. M. Hogervorst, M. H. M. Wauben, R. van der Zee, J. D. A. van Embden
      Pages 167-179

    3. Type-II Collagen in the Pathogenesis of Rheumatoid Arthritis

      • R. Holmdahl
      Pages 180-201

    4. Streptococcal Cell Wall Antigens and Rheumatoid Arthritis

      • L. J. Crofford, R. L. Wilder
      Pages 202-215

    5. Caprine Arthritis-Encephalitis

      • E. Peterhans, B. Pohl, R. Zanoni, S. Lazary
      Pages 216-230
Back to top

Keywords

About this book

Many advances have occurred in the last 5 years especially in understanding genetic susceptibility factors, the role of immune response in chronic arthritis and the relationship between cellular processes that underlie inflammation and tissue damage. All these are dealt with in depth in the individual contributions. Genetics studies included illustrate how studies of HLA genes and genes controlling the autoantibody repertoire may be involved. Environmental factors are believed to be important and studies both in humans and in experimental models on the role of viral and bacterial agents are covered. The fascinating relationship between microbes, dysregulated immune responses and oncogenes are also examined. Since autoimmunity is the key aspect of the immunological response in rheumatoid arthritis, the role of antigens is re-examined as is the part played by immune T and B cells. New areas of clinical application of basic science is well presented in this book, forexample, in examining how markers of cartilage destruction may become important in monitoring disease activity. A chapter reviewing possible future novel therapies is included.

Editors and Affiliations

  • 2. Medizinische Abteilung Zentrum fü Diagnostik und Therapie rheumatischer Erkrankungen, Krankenhaus der Stadt Wien-Lainz und Ludwig Boltzmann Institut für Rheumatologie und Balneologie, Wien, Austria

    Josef S. Smolen

  • Medizinische Klinik III mit Poliklinik und Institut für Klinische Immunologie und Rheumatologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

    Joachim R. Kalden

  • Mathilda and Terence Kennedy Institute of Rheumatology, Hammersmith, London, UK

    Ravinder N. Maini

Bibliographic Information

  • Book Title: Rheumatoid Arthritis

  • Book Subtitle: Recent Research Advances

  • Editors: Josef S. Smolen, Joachim R. Kalden, Ravinder N. Maini

  • DOI: https://doi.org/10.1007/978-3-642-76189-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1992

  • Softcover ISBN: 978-3-642-76191-1Published: 21 December 2011

  • eBook ISBN: 978-3-642-76189-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XX, 399

  • Topics: Rheumatology, Immunology, Orthopedics

Publish with us

Policies and ethics

Back to top

Search

Navigation