Current Topics in Microbiology and Immunology

The Role of Viruses and the Immune System in Diabetes Mellitus

Experimental Models

Editors: Dyrberg, Thomas (Ed.)

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About this book

Research in diabetes has accelerated in two areas, both of which are being reviewed in CTMI. The first is the use of a variety of animal models; the second is basic research in human investigation, islet cell antigens, and mapping of genes as­ sociated with susceptibility to disease. Dr. Thomas Dyrberg accepted editorial responsibility for this volume, which covers the first area. A second book, to be published later in the year, is edited by Drs. Brekkeskov and Hansen (CTMI 164, see page VI for contents). Although the contributors to both volumes represent the international scientific community, the editors are from the Hagedorn Research Laboratory in Denmark. Work at this institute and the Steno Memorial Hospital has been dedicated to research in diabetes for decades, and the insti­ tutions were appointed WHO Collaborating Centres for Re­ search and Training on the Pathogenesis of Diabetes Mellitus in 1983. It is worth noting that while addressing the hypothesis of the role of class II major histocompatibility glycoproteins in autoimmune diabetes (insulin-dependent diabetes, IDDM) a number of investigators established animal models in which class II molecules were expressed under the control of the rat insulin promoter. While generating interesting information on 100M, the finding of immunologic tolerance in such transgenic mice has attracted the attention of several basic immunologic laboratories for quite different reasons. Thus, we are reminded again of the Pasteur dictum that "chance favors the prepared mind. " Michael B. A. Oldstone, M. D.

Table of contents (9 chapters)

Table of contents (9 chapters)

Buy this book

eBook 106,99 €
price for Spain (gross)
  • ISBN 978-3-642-75239-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 135,19 €
price for Spain (gross)
  • ISBN 978-3-642-75241-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
The Role of Viruses and the Immune System in Diabetes Mellitus
Book Subtitle
Experimental Models
Editors
  • Thomas Dyrberg
Series Title
Current Topics in Microbiology and Immunology
Series Volume
156
Copyright
1990
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-75239-1
DOI
10.1007/978-3-642-75239-1
Softcover ISBN
978-3-642-75241-4
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XI, 139
Number of Illustrations
6 b/w illustrations
Topics