Reactivity and Structure: Concepts in Organic Chemistry

Organotitanium Reagents in Organic Synthesis

Authors: Reetz, Manfred

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About this book

Titanium has been used to perform many kinds of reactions in organic and inorganic chemistry. The present book is concerned primarily with a new development in titanium chemistry which is useful in organic synthesis. In 1979/80 it was discovered that the titanation of classical carbanions using C1TiX leads to species with reduced basicity and reactivity. This increases 3 chemo-, regio-and stereo selectivity in reactions with organic compounds such as aldehydes, ketones and alkyl halides. Many new examples have been reported in recent times. Since the nature of the ligand X at titanium can be widely varied, the electronic and steric nature of the reagents is easily controlled. This helps in predicting the stereochemical outcome of many of the C-C bond forming reactions, but the trial and error method is still necessary in other cases. One of the ultimate objectives of chemistry is to understand correlations between structure and reactivity. Although this goal has not been reached in the area of organotitanium chemistry, appreciable progress has been made. A great deal of physical and computational data of organotitanium compounds described in the current and older literature (e. g. , Ziegler-Natta type catalysts) has been reported by polymer, inorganic and theoretical chemists. It is summarized in Chapter 2 of this book, because some aspects are useful in understanding reactivity and selectivity of organo­ titanium compounds in organic synthesis as described in the chapters which follow.

Table of contents (8 chapters)

Table of contents (8 chapters)

Buy this book

eBook 74,89 €
price for Spain (gross)
  • ISBN 978-3-642-70704-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 93,59 €
price for Spain (gross)
  • ISBN 978-3-642-70706-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Organotitanium Reagents in Organic Synthesis
Authors
Series Title
Reactivity and Structure: Concepts in Organic Chemistry
Series Volume
24
Copyright
1986
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-70704-9
DOI
10.1007/978-3-642-70704-9
Softcover ISBN
978-3-642-70706-3
Series ISSN
0341-2377
Edition Number
1
Number of Pages
X, 236
Topics