Research and Perspectives in Alzheimer's Disease

Connections, Cognition and Alzheimer’s Disease

Editors: Hyman, Bradley T., Duyckaerts, Charles (Eds.)

Free Preview

Buy this book

eBook 96,29 €
price for Spain (gross)
  • ISBN 978-3-642-60680-9
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 126,35 €
price for Spain (gross)
  • ISBN 978-3-642-64504-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

The fundamental relationship between the neuropathological lesions of Alzheimer's disease and the problem of what underlies the clinical syndrome has remained unsolved since the beginning of the century. Are neurofibrillary tangles and senile plaques directly related to clinical symptoms, or are they epiphenomena that signal synaptic and neuronal loss? In the last decade, these questions have been revisited through systematic studies of individuals with various degrees of dementia using newer immunohistochemical techniques and quantitative approaches to neuropathological study. It is now possible to have a uniform picture of Alzheimer's disease dementia as resulting from collapse of specific neural systems, as pathological changes selectively and specifically involve structures related to memory and higher cognitive functions.This book contains the proceedings of a meeting organized by the Fondation Ipsen which brought together researchers in neuropathology, molecular biology, genetics, neuropsychology, brain imagery and clinical neurology. .

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Aspects of Cortical Destruction in Alzheimer’s Disease

    Pages 1-16

    Braak, H. (et al.)

  • Cortical Feedforward and Cortical Feedback Neural Systems in Alzheimer’s Disease

    Pages 17-31

    Hoesen, G. W.

  • Plaques and Tangles: Where and When?

    Pages 33-39

    Duyckaerts, C. (et al.)

  • Cortical Mapping of Pathological Tau Proteins in Several Neurodegenerative Disorders

    Pages 41-52

    Vermersch, P. (et al.)

  • Neurofibrillary Tangles are Associated with the Differential Loss of Message Expression for Synaptic Proteins in Alzheimer’s Disease

    Pages 53-57

    Callahan, Linda (et al.)

Buy this book

eBook 96,29 €
price for Spain (gross)
  • ISBN 978-3-642-60680-9
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 126,35 €
price for Spain (gross)
  • ISBN 978-3-642-64504-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
Loading...

Bibliographic Information

Bibliographic Information
Book Title
Connections, Cognition and Alzheimer’s Disease
Editors
  • Bradley T. Hyman
  • Charles Duyckaerts
Series Title
Research and Perspectives in Alzheimer's Disease
Copyright
1997
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-60680-9
DOI
10.1007/978-3-642-60680-9
Softcover ISBN
978-3-642-64504-4
Series ISSN
0945-6066
Edition Number
1
Number of Pages
XIV, 194
Topics