Overview
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 367)
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Table of contents (11 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Regeneration, the homeostatic ability to maintain tissue structure in the face of normal cell turnover or loss of tissue damaged by trauma or disease, is an essential developmental process that continues throughout life. As recently as a decade ago, any serious discussion of the possibility of regeneration becoming a practical medical tool in the near future had the air of science fiction or over-optimistic speculation. The term “regenerative medicine” was certainly on many lips but few actually expected to soon see it applied in a clinical setting. A tidal wave of discovery has changed that and investigating the cellular mechanisms of natural regeneration has become one of the hottest topics in developmental biology and biomedicine in general. Many researchers entering the field find that the regeneration literature is still quite diffuse perhaps owing to the disparate biological systems that have been the object of study including hydra, planaria, newts, axolotls and more recently several mouse strains. The volume editors believe that an attempt to organize or systematize the literature is long overdue. In this volume, respected experts highlight the latest findings in vertebrate (including mammals) wound healing and regeneration. They present eleven reviews that cover a wide range of topics, from wound repair and its relationship to regeneration, through systems including lenticular, neural, and musculoskeletal tissues and limbs, to epigenetics and the role of the cellcycle. Nuclear reprogramming and cellular plasticity, which open the door for potential regenerative medical therapies for injury and degenerative disease, are recurring themes throughout the book. We are all now part of the regeneration revolution.
Reviews
“This is an outstanding textbook about limb bud regeneration into fully functional limbs in fish, mammals, and amphibian species. … The operative signaling including full color microscopic images and diagrams is provided. I highly commend it for all devoted scientists.” (Joseph J. Grenier, Amazon.com, September, 2015)
Editors and Affiliations
Bibliographic Information
Book Title: New Perspectives in Regeneration
Editors: Ellen Heber-Katz, David L. Stocum
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-642-35810-4
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2013
Hardcover ISBN: 978-3-642-35809-8Published: 11 April 2013
Softcover ISBN: 978-3-642-43081-7Published: 04 April 2015
eBook ISBN: 978-3-642-35810-4Published: 08 July 2014
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: X, 281
Topics: Human Physiology, Human Genetics, Neurosciences, Regenerative Medicine/Tissue Engineering, Developmental Biology