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  • © 2012

Investigation of Reactions Involving Pentacoordinate Intermediates

The Mechanism of the Wittig Reaction

Authors:

  • Nominated by University College Dublin as an outstanding PhD thesis
  • Describes the first example of an effect common to examples of all Li salt-free Wittig reactions
  • Outlines the development of a new chromatography-free method for the removal of phosphine oxide from the alkene crude product of the Wittig reaction
  • Includes supplementary material: sn.pub/extras
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Theses (Springer Theses)

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Table of contents (4 chapters)

About this book

In this thesis, the author outlines the discovery of an effect common to representative examples of all Li salt-free Wittig Reactions. The implications of such a universally applicable effect are that all such Wittig reactions occur through the same mechanism. Although the Wittig reaction was first discovered in 1953, its reaction mechanism has never been definitively settled with many different variants proposed and disproved. The work in this thesis shows conclusively that for [2+2] cycloadditions all Wittig reactions occur by the same irreversible mechanism. In addition, the author also describes a new chromatography-free method for the removal of phosphine oxide from the alkene crude product of the Wittig reaction. The work in this thesis has led to several publications in high-profile journals.

Authors and Affiliations

  • , School of Chemistry and Chemical Biology, University College Dublin, Dublin 4, Ireland

    Peter A. Byrne

Bibliographic Information

  • Book Title: Investigation of Reactions Involving Pentacoordinate Intermediates

  • Book Subtitle: The Mechanism of the Wittig Reaction

  • Authors: Peter A. Byrne

  • Series Title: Springer Theses

  • DOI: https://doi.org/10.1007/978-3-642-32045-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2012

  • Hardcover ISBN: 978-3-642-32044-6Published: 07 February 2013

  • Softcover ISBN: 978-3-642-43787-8Published: 07 March 2015

  • eBook ISBN: 978-3-642-32045-3Published: 01 February 2013

  • Series ISSN: 2190-5053

  • Series E-ISSN: 2190-5061

  • Edition Number: 1

  • Number of Pages: XVI, 231

  • Number of Illustrations: 8 b/w illustrations, 25 illustrations in colour

  • Topics: Organic Chemistry, Theoretical and Computational Chemistry, Analytical Chemistry

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access