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Deep Brain Stimulation

A New Frontier in Psychiatry

  • Book
  • © 2012

Overview

Editors:
  1. Damiaan Denys

    1. , Department of Psychiatry, Academic Medical Center, University of A, Amsterdam, Netherlands

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    You can also search for this editor in PubMed   Google Scholar

  2. Matthijs Feenstra

    1. , Neuromodulation and Behaviour, Netherlands Institute for Neuroscience, Amsterdam, Netherlands

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    You can also search for this editor in PubMed   Google Scholar

  3. Rick Schuurman

    1. , Department of Neurosurger, Academic Medical Center, University of A, Amsterdam, Netherlands

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • First book compiling papers on this specific therapy and technique

  • With contributions from the world’s leading experts in the field

  • Clinical application and animal research is presented side-by-side to provide a true translational approach.

  • Written for psychiatrists, neuroscientists, and neurobiologists in research and practice

  • Includes supplementary material: sn.pub/extras

  • Includes supplementary material: sn.pub/extras

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Basic Principles of Deep Brain Stimulation

    • F. L. H. Gielen, G. C. Molnar
    Pages 1-10

  3. Neural Circuits Affected by Deep Brain Stimulation for the Treatment of Psychiatric Disorders

    • Suzanne N. Haber, Benjamin D. Greenberg
    Pages 11-20

  4. Mechanisms of Action of Deep Brain Stimulation for the Treatment of Psychiatric Disorders

    • J. Luis Lujan, Cameron C. McIntyre
    Pages 21-33

  5. Deep Brain Stimulation in the Ventral Capsule/Ventral Striatum for the Treatment of Obsessive–Compulsive Disorder: Role of the Bed Nucleus of the Stria Terminalis

    • Loes Gabriëls, Bart Nuttin
    Pages 35-41

  6. Deep Brain Stimulation in Obsessive–Compulsive Disorder Targeted at the Nucleus Accumbens

    • Pelle P. de Koning, Pepijn van den Munckhof, Martijn Figee, Rick Schuurman, Damiaan Denys
    Pages 43-51

  7. What is the Role of the Subthalamic Nucleus in Obsessive–Compulsive Disorder? Elements and Insights from Deep Brain Stimulation Studies

    • William I. A. Haynes, Luc Mallet
    Pages 53-60

  8. Obsessive–Compulsive Disorders in Animals

    • Christine Winter
    Pages 61-70

  9. Subcallosal Cingulate Cortex Deep Brain Stimulation for the Treatment of Refractory Mood Disorders: Evidence and Challenges

    • Peter Giacobbe, Nir Lipsman, Andres M. Lozano
    Pages 71-79

  10. Deep Brain Stimulation of the Human Reward System as a Putative Treatment for Refractory Major Depression

    • T. E. Schlaepfer, V. A. Coenen, B. H. Bewernick
    Pages 81-93

  11. Depression in Humans: The Ventral Capsule/Ventral Striatum

    • Mayur Pandya, Andre Machado, Donald Malone
    Pages 95-102

  12. Deep Brain Stimulation in Animal Models of Depression

    • Brian W. Scott, José N. Nobrega, Clement Hamani
    Pages 103-112

  13. Deep Brain Stimulation in Tourette Syndrome

    • L. Ackermans, I. Neuner, J. Kuhn, V. Visser-Vandewalle
    Pages 113-129

  14. Surgical Treatments for Drug Addictions in Humans

    • Bomin Sun, Wei Liu
    Pages 131-140

  15. Manipulating Addictive Behaviour in Animal Models

    • Rolinka M. C. Schippers, Tommy Pattij, Taco J. De Vries
    Pages 141-157

  16. Neuropsychiatric Side Effects of Deep Brain Stimulation in Parkinson’s Disease

    • Christine Daniels, Jens Volkmann
    Pages 159-173

  17. Psychiatric Aspects of Parkinson’s Disease in Animal Models of Deep Brain Stimulation of the Subthalamic Nucleus

    • S. K. H. Tan, H. Hartung, V. Visser-Vandewalle, T. Sharp, Y. Temel
    Pages 175-182

  18. Scientific Recordings in Deep Brain Stimulation

    • Michael X. Cohen
    Pages 183-191

  19. Neurotransmitter Release During Deep Brain Stimulation

    • Osama A. Abulseoud, Emily J. Knight, Kendall H. Lee
    Pages 193-204

  20. The Potential Role of Nonneuronal Cells in the Deep Brain Stimulation Mechanism

    • Vinata Vedam-Mai, Michael S. Okun, Elly M. Hol
    Pages 205-215
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Keywords

About this book

Deep Brain Stimulation: A New Frontier in Psychiatry provides an overview of current developments and the future possibilities of deep brain stimulation for patients with therapy-refractory psychiatric disorders. The side-by-side presentation of clinical applications and animal research provides a truly translational approach. Also included is a special chapter on the ethical issues involved in deep brain stimulation in psychiatry.

Deep brain stimulation of selected brain areas has been shown to result in a substantial improvement of symptoms and quality of life in patients suffering from obsessive-compulsive disorder, major depressive disorder and drug addiction. Although it is still an experimental therapy and the number of psychiatric patients that are treated is low, its effectiveness and safety makes deep brain stimulation the most promising therapy for treating other serious and life-threatening psychiatric conditions.

Editors and Affiliations

  • , Department of Psychiatry, Academic Medical Center, University of A, Amsterdam, Netherlands

    Damiaan Denys

  • , Neuromodulation and Behaviour, Netherlands Institute for Neuroscience, Amsterdam, Netherlands

    Matthijs Feenstra

  • , Department of Neurosurger, Academic Medical Center, University of A, Amsterdam, Netherlands

    Rick Schuurman

Bibliographic Information

  • Book Title: Deep Brain Stimulation

  • Book Subtitle: A New Frontier in Psychiatry

  • Editors: Damiaan Denys, Matthijs Feenstra, Rick Schuurman

  • DOI: https://doi.org/10.1007/978-3-642-30991-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2012

  • Hardcover ISBN: 978-3-642-30990-8Published: 13 September 2012

  • Softcover ISBN: 978-3-642-43470-9Published: 15 October 2014

  • eBook ISBN: 978-3-642-30991-5Published: 14 September 2012

  • Edition Number: 1

  • Number of Pages: XII, 300

  • Topics: Neurosciences, Psychiatry, Neurobiology

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