Metabolomics
A Powerful Tool in Systems Biology
Editors: Nielsen, Jens, Jewett, Michael C. (Eds.)
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- Offers real strategies for understanding cellular complexity
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- About this book
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The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated to a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g. protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms.
This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.
- Table of contents (10 chapters)
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The role of metabolomics in systems biology
Pages 1-10
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Analytical methods from the perspective of method standardization
Pages 11-52
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Reporting standards
Pages 53-73
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The Golm Metabolome Database: a database for GC-MS based metabolite profiling
Pages 75-95
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Reconstruction of dynamic network models from metabolite measurements
Pages 97-127
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Table of contents (10 chapters)
- Download Sample pages 1 PDF (366.1 KB)
- Download Table of contents PDF (308.6 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Metabolomics
- Book Subtitle
- A Powerful Tool in Systems Biology
- Editors
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- Jens Nielsen
- Michael C. Jewett
- Series Title
- Topics in Current Genetics
- Series Volume
- 18
- Copyright
- 2007
- Publisher
- Springer-Verlag Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- eBook ISBN
- 978-3-540-74719-2
- DOI
- 10.1007/978-3-540-74719-2
- Hardcover ISBN
- 978-3-540-74718-5
- Softcover ISBN
- 978-3-642-09418-7
- Series ISSN
- 1610-2096
- Edition Number
- 1
- Number of Pages
- XVI, 284
- Number of Illustrations
- 40 b/w illustrations, 13 illustrations in colour
- Topics
