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Proton Therapy and Radiosurgery

  • Book
  • © 2000

Overview

Authors:
  1. Hans Breuer

    1. Stellenbosch, Rep. of South Africa

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  2. Berend J. Smit

    1. Department of Radiation Oncology, Tygerberg Hospital, Tygerberg, Rep. of South Africa

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    You can also search for this author in PubMed   Google Scholar

  • Proton therapy is the radiotherapy modality of the future already available in many centres and soon can be expected in the clinics
  • Relativeley inexpensive dedicated particle accelerators are entering the hospitals now. Proton therapy is emering as the "winner" and such a practical text is urgently needed in this fast developing field

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Table of contents (16 chapters)

  1. Front Matter

    Pages I-XVI
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  2. Radiation Physics

    1. Front Matter

      Pages 1-1
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    2. General Aspects

      • Hans Breuer, Berend J. Smit
      Pages 3-5

    3. Basics

      • Hans Breuer, Berend J. Smit
      Pages 7-19

    4. Interaction of Protons with Matter

      • Hans Breuer, Berend J. Smit
      Pages 21-53

    5. Modifying the Proton Beam

      • Hans Breuer, Berend J. Smit
      Pages 55-66

    6. Conformal Proton Radiotherapy Planning

      • Hans Breuer, Berend J. Smit
      Pages 67-88

  3. Proton Therapy and Radiosurgery

    1. Front Matter

      Pages 93-93
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    2. General Aspects of Proton Therapy

      • Hans Breuer, Berend J. Smit
      Pages 95-109

    3. The Rationale for Proton Therapy

      • Hans Breuer, Berend J. Smit
      Pages 111-120

    4. Radiobiology

      • Hans Breuer, Berend J. Smit
      Pages 121-146

    5. Dose-Volume Relationships in Proton Therapy and Radiosurgery for Arteriovenous Malformations, Skull Base Meningiomas and Recurrent Malignant Gliomas

      • Hans Breuer, Berend J. Smit
      Pages 147-164

    6. Low Energy Proton Beam Therapy for Eye Lesions

      • Hans Breuer, Berend J. Smit
      Pages 165-179

    7. High Energy Proton Therapy for Tumours in Body Sites Other than the Brain

      • Hans Breuer, Berend J. Smit
      Pages 181-195

    8. Radiosurgical Applications of Protons and Photons

      • Hans Breuer, Berend J. Smit
      Pages 197-245

    9. The Complications of Single Large Intracranial Doses of Radiation and Their Management

      • Hans Breuer, Berend J. Smit
      Pages 247-257

    10. Alternatives to Proton Therapy for Radiosurgery

      • Hans Breuer, Berend J. Smit
      Pages 259-267

    11. Costs of Proton Therapy and Radiosurgery

      • Hans Breuer, Berend J. Smit
      Pages 269-273

    12. Appendix

      • Hans Breuer, Berend J. Smit
      Pages 275-284

  4. Back Matter

    Pages 285-288
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Keywords

About this book

The book is divided into two parts: Part I deals with the relevant physics and planning algorithms of protons (H Breuer) and Part II with the radiobiology, radiopathology and clinical outcomes of proton therapy and a comparison of proton therapy versus photon therapy (BJ Smit). Protons can be used for radiosurgery and general radio­ therapy. Since proton therapy was first proposed in 1946 by Wilson, about sixteen facilities have been built globally. Only a very few of these have isocentric beam delivery systems so that proton therapy is really only now in a position to be compared directly by means of randomised clinical trials, with modern photon radiotherapy therapy sys­ tems, both for radiosurgery and for general fractionated radiotherapy. Three-dimensional proton planning computer systems with image fusion (image of computerised tomography (CT), magnetic resonance registration) capabilities imaging (MRI), stereotactic angiograms and perhaps positron emission tomography (PET) are essential for accurate proton therapy planning. New planning systems for spot scanning are under development. Many of the older comparisons of the advantageous dose distributions for protons were made with parallel opposing or multiple co-planar field arrangements, which are now largely obsolete. New comparative plans are necessary once more because of the very rapid progress in 3-D conformal planning with photons. New cost-benefit analy­ ses may be needed. Low energy (about 70 MeV) proton therapy is eminently suitable for the treatment of eye tumours and has firmly established itself as very useful in this regard.

Authors and Affiliations

  • Stellenbosch, Rep. of South Africa

    Hans Breuer

  • Department of Radiation Oncology, Tygerberg Hospital, Tygerberg, Rep. of South Africa

    Berend J. Smit

Bibliographic Information

  • Book Title: Proton Therapy and Radiosurgery

  • Authors: Hans Breuer, Berend J. Smit

  • DOI: https://doi.org/10.1007/978-3-662-04301-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2000

  • Hardcover ISBN: 978-3-540-64100-1Published: 16 December 1999

  • Softcover ISBN: 978-3-642-08379-2Published: 07 December 2010

  • eBook ISBN: 978-3-662-04301-1Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: XVI, 288

  • Topics: Oncology, Imaging / Radiology, Radiotherapy

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