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  • © 2018

HSP70 in Human Diseases and Disorders

  • Combines studies of the role of HSP70 in Human Diseases and Disorders
  • Contains colored photos of unique model systems
  • Is easy to read and understand for professionals in the field
  • Written by eminent HSP researchers performing clinical-, basic- and translational research
  • Covers HSP70 in onco-neurology, circulatory and as a therapeutic target

Part of the book series: Heat Shock Proteins (HESP, volume 14)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-ix
  2. Hsp70 in Neuro-oncological Disorders

    1. Front Matter

      Pages 1-1
    2. Heat Shock Protein 70 and Molecular Confession During Neurodegeneration

      • Komal Panchal, Ajay Kumar, Anand K. Tiwari
      Pages 3-35
    3. Hsp70-Family Proteins and Neurodegenerative Diseases

      • Zheying Sun, Roy J. Blackburn, Laura J. Blair, John Koren III
      Pages 37-55
    4. Heat Shock Protein70 in Neurological Disease

      • Pinar Ortan, Ozden Yildirim Akan, Ferda Hosgorler
      Pages 57-69
    5. Involvement of Heat Shock Protein 70 (Hsp70) in Gastrointestinal Cancers

      • Dipamoy Datta, Suparna Banerjee, Anupama Ghosh, Soumyajit Banerjee Mustafi, Prosenjit Sen, Sanghamitra Raha
      Pages 71-91
    6. Heat Shock Protein 70 and Cancer

      • Tuoen Liu, Shousong Cao
      Pages 93-111
    7. Implication of HSP70 in the Pathogenesis of Gastric Cancer

      • Prakash Chand Sharma, Renu Verma
      Pages 113-130
  3. Hsp70 in Circulatory Disorders

    1. Front Matter

      Pages 131-131
    2. Double Face of eHsp70 in Front of Different Situations

      • Maria M. Barreca, Fabiana Geraci
      Pages 133-161
    3. HSP70 Is a Major Contributor to the MHCII Ligandome and Inducer of Regulatory T Cells

      • Willem van Eden, Femke Broere, Ruurd van der Zee
      Pages 163-171
    4. Immune Properties of HSP70

      • Yves Delneste, Vincent Larochette, Pascale Jeannin
      Pages 173-203
    5. Molecular Chaperones Regulating the Dynamics, Composition and Functionality of RNP Granules: Implications for Age-Related Diseases

      • Daniel Mateju, Laura Mediani, Federica F. Morelli, Simon Alberti, Serena Carra
      Pages 205-222
    6. Heat Shock Proteins in Cardiovascular Diseases: From Bench to Bedside

      • Francesca Bonomini, Gaia Favero, Valentina Trapletti, Rita Rezzani
      Pages 223-245
    7. Clinical Implication of Heat Shock Protein 70 in Kidney Disease

      • Alev Yilmaz, Zeynep Nagehan Yuruk Yildirim
      Pages 247-260
    8. Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retina

      • Ting Zhang, Bobak Bahrami, Ling Zhu
      Pages 273-287
  4. Hsp70 as a Therapeutic Target

    1. Front Matter

      Pages 289-289
    2. Emerging Role of HSP70 in Human Diseases

      • Anjali Garg, Bandana Kumari, Manish Kumar
      Pages 291-304
    3. Intranasal Administration of Hsp70: Molecular and Therapeutic Consequences

      • Michael B. Evgen’ev, David G. Garbuz, Alexei V. Morozov, Natalia V. Bobkova
      Pages 305-323

About this book

The book HSP70 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP70 family - one of the most studied HSP - in human diseases and disorders. Using an integrative approach to expand our current understanding of HSP70 functions, the contributors provide a synopsis of novel mechanisms by which HSP70 is involved in the regulation of human diseases and disorders. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for medical students and residents, clinical and basic science researchers, postdoctoral fellows and graduate students in the fields of Medicine, Physiology, Clinical Trials, Biotechnology, Molecular Medicine and Pathology.


Editors and Affiliations

  • Department of Medicine and Precision Therapeutics Proteogenomics Diagnostic Center, Eleanor N. Dana Cancer Center, University of Toledo College of Medicine and Life Sciences, Toledo, USA

    Alexzander A. A. Asea

  • Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA

    Punit Kaur

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access