Multidisciplinary Approach to Osteoporosis

1. Front Matter

   Pages i-viii

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2. Anatomy and Physiology of Skeletal Tissue: The Bone Cells

   • Giacomina Brunetti, Graziana Colaianni, Silvia Colucci, Maria Grano

   Pages 1-23

3. Genetics of Osteoporosis

   • Francesca Marini, Laura Masi, Gemma Marcucci, Luisella Cianferotti, Maria Luisa Brandi

   Pages 25-44

4. Osteoporosis Diagnosis

   • Claudio Marcocci, Federica Saponaro

   Pages 45-57

5. Functional Evaluation of the Subjects with Skeletal Alterations

   • Giovanni Iolascon, Alessandro de Sire, Marco Paoletta, Antimo Moretti, Francesca Gimigliano

   Pages 59-71

6. Endocrinologicic and Metabolic Regulation

   1. Front Matter

      Pages 73-73

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   2. Skeletal Alterations and Parathyroid Function

      • Elisabetta Romagnoli, Vincenzo Carnevale

      Pages 75-82

   3. GH/IGF-I and Bone

      • Stefano Frara, Filippo Maffezzoni, Mauro Doga, Anna Maria Formenti, Gherardo Mazziotti, Andrea Giustina

      Pages 83-106

   4. Adrenal Function and Skeletal Regulation

      • Iacopo Chiodini, Claudia Battista, Elisa Cairoli, Cristina Eller-Vainicher, Valentina Morelli, Serena Palmieri et al.

      Pages 107-128

   5. Skeletal Tissue and Ovarian Function: Puberty and Menopause

      • Annamaria Colao, Carolina Di Somma, Volha V. Zhukouskaya

      Pages 129-142

   6. Obesity and Osteoporosis: Is the Paradigm Changing?

      • Emanuela A. Greco, Rachele Fornari, Andrea Lenzi, Silvia Migliaccio

      Pages 143-152

   7. Bone and Diabetes

      • Andrea Palermo, Anda Mihaela Naciu, Gaia Tabacco, Luca D’Onofrio, Nicola Napoli

      Pages 153-182

   8. Renal Diseases and Skeletal Health

      • Sandro Mazzaferro, Silverio Rotondi, Lida Tartaglione, Natalia De Martino, Cristiana Leonangeli, Marzia Pasquali

      Pages 183-209

   9. Osteoporosis and Cardiovascular Risk

      • Giancarlo Isaia, Lorenzo Marchese, Margherita Marchetti, Mario Bo

      Pages 211-221

   10. Osteoporosis in Men

       • Elena Nebot Valenzuela, Peter Pietschmann

       Pages 223-235

   11. Rheumatic Diseases and Osteoporosis

       • Ombretta Di Munno, Nazzarena Malavolta, Giovanni Minisola

       Pages 237-255

7. Prevention and Treatment

   1. Front Matter

      Pages 257-257

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   2. Nutrition and Skeletal Health

      • Chiara Marocco, Rachele Fornari, Andrea Lenzi, Emanuela A. Greco

      Pages 259-276

   3. Different Physical Activity Protocols in the Subjects Affected by Osteoporosis

      • Gian Pietro Emerenziani, Emanuela A. Greco, Laura Guidetti, Carlo Baldari

      Pages 277-284

   4. Pharmacological Therapy: Past, Present, and Future

      • Silvia Migliaccio, Andrea Lenzi, Emanuela A. Greco

      Pages 285-295

This book describes in detail the multidisciplinary management of osteoporosis, providing readers with a thorough understanding of the rationale for a multidisciplinary approach and with the tools required to implement it effectively. The emphasis is on a translational approach, starting from basic concepts and fundamental mechanisms of the pathology and clinical morbidity. Experts in the field discuss the full range of relevant topics, including the significance of physical activity, nutritional strategies, and pharmacological treatment. Put another way, the book covers all aspects from the bench to the bedside. Physicians, scientists, and postgraduate students will all find it to be invaluable in understanding the causes and optimal management of osteoporosis, the incidence of which is increasing rapidly as populations age.  

• Metabolism
• Nutrition
• Physical exercise
• Diagnosis
• Treatment
• Prevention
• metabolic disease

• Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy

  Andrea Lenzi

• Department of Movement, Human and Health Sciences, Foro Italico University of Rome, Rome, Italy

  Silvia Migliaccio

Andrea Lenzi is Full Professor of Endocrinology in the Department of Experimental Medicine, University of Rome “Sapienza”, Rome, Italy. He is Director of the Unit of Andrology, Reproductive Physiopathology, and Endocrine Diagnosis and Coordinator of Laboratories of Endocrinology at the Policlinico Umberto I University Hospital, Rome, Italy. Dr. Lenzi is President of the Italian National University Council and Director of the Interuniversity Research Centre for Experimental Andrology (CASPER). He has served as Secretary General of the International Society for Immunology of Reproduction (1999-2004), the Alps-Adria Society for Immunology of Reproduction (1998-2001), and the Executive Council of the European Academy of Andrology (2002-2010). Dr. Lenzi has also been President of the Italian Society of Andrology and Medical Sexology (2008-2010). He is a member of the editorial boards of several international scientific journals and has published more than 220 original papers in the main international journals in the field.


Silvia Migliaccio is Researcher in the Department of Movement, Human and Health Sciences, University of Rome “Foro Italico”, Rome, Italy. He is Coordinator of the Unit of Osteoporosis and Bone Metaboli Diseases t the Policlinico Umberto I University Hospital, Rome Italy. Dr. Migliaccio’s many previous positions have included Visiting Asoociate at the National Institute of Environmental Health Sciences, North Carolina, USA. She has served as Member of the Executive Council of the Italian Society of Osteoporosis and Skeletal Diseases (SIOMMMS) and she is member of the Executive Council of the Italian Society of Nutrition (S.I.S.A.). She has published more than 100 original papers in the main international and national journals in the field of skeletal metabolism, nutrition and metabolic disorders.

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