Regression Analysis in Medical Research
for Starters and 2nd Levelers
Authors: Cleophas, Ton J., Zwinderman, Aeilko H.
Free Preview  covers major fields of regression analysis
  stepbystep analyses for selfassessment
  using applications in medical and health research
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 About this Textbook

This edition is a pretty complete textbook and tutorial for medical and health care students, as well as a recollection/update bench, and help desk for professionals. Novel approaches already applied in published clinical research will be addressed: matrix analyses, alpha spending, gate keeping, kriging, interval censored regressions, causality regressions, canonical regressions, quasilikelihood regressions, novel nonparametric regressions. Each chapter can be studied as a standalone, and covers one field in the fast growing world of regression analyses.
The authors, as professors in statistics and machine learning at European universities, are worried, that their students find regressionanalyses harder than any other methodology in statistics. This is serious, because almost all of the novel methodologies in current data mining and data analysis include elements of regressionanalysis. It is the main incentive for writing this 28 chapter edition, consistent of
 28 major fields of regression analysis,
 their condensed maths,
 their applications in medical and health research as published so far,
 step by step analyses for selfassessment,
 conclusion and reference sections.
Traditional regression analysis is adequate for epidemiology, but lacks the precision required for clinical investigations. However, in the past two decades modern regression methods have proven to be much more precise. And so it is time, that a book described regression analyses for clinicians. The current edition is the first to do so. It is written for a nonmathematical readership. Selfassessment datafiles are provided through Springer' s "Extras Online".
 About the authors

The authors are wellqualified in their field. Professor Zwinderman is pastpresident of the International Society of Biostatistics (20122015), and Professor Cleophas is pastpresident of the American College of Angiology (20002002).
Professor Zwinderman is one of the Principle Investigators of the Academic Medical Center Amsterdam, and his research is concerned with developing statistical methods for new research designs in biomedical science, particularly integrating omics data, like genomics, proteomics, metabolomics, and analysis tools based on parallel computing and the use of cluster computers and grid computing.
Professor Cleophas is a member of the Academic Committee of the European College of Pharmaceutical Medicine, that provides, on behalf of 22 European Universities, the Mastership trainings "Pharmaceutical Medicine" and "Medicines Development".
From their expertise they should be able to make adequate selections of modern methods for clinical data analysis for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 18 years, and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.
The authors as professors and teachers in statistics at universities in The Netherlands and France for the most part of their lives, are concerned, that their students find regressionanalyses harder than any other methodology in statistics. This is serious, because almost all of the novel methodologies in current data mining and data analysis include elements of regressionanalysis, and they do hope that the current production "Regression Analysis for Starters and 2nd Levelers" will be a helpful companion for the purpose. Five textbooks complementary to the current production and written by the same authors are
Statistics applied to clinical studies 5th edition, 2012, Machine learning in medicine a complete overview, 2015, SPSS for starters and 2nd levelers 2nd edition, 2015, Clinical data analysis on a pocket calculator 2nd edition, 2016, Modern Metaanalysis, 2017, all of them published by Springer  Reviews

“This is a comprehensive book on various types of theoretical, basic, and applied regression analysis in medical research. … There are sufficient examples in each chapter to enable better understanding of theory. … Each chapter has numerous graphs and tables, which are easy to understand and nicely detailed. This is an excellent reference for medical students, researchers in medicine, and healthcare professionals who want either a basic or an advanced understanding and interpretation of all types of regression analysis.” (Timir Paul, Doody's Book Reviews, April, 2018)
 Table of contents (26 chapters)


Continuous Outcome Regressions
Pages 139

Dichotomous Outcome Regressions
Pages 4159

Confirmative Regressions
Pages 6173

Dichotomous Regressions Other Than Logistic and Cox
Pages 75103

Polytomous Outcome Regressions
Pages 105129

Table of contents (26 chapters)
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Bibliographic Information
 Bibliographic Information

 Book Title
 Regression Analysis in Medical Research
 Book Subtitle
 for Starters and 2nd Levelers
 Authors

 Ton J. Cleophas
 Aeilko H. Zwinderman
 Copyright
 2018
 Publisher
 Springer International Publishing
 Copyright Holder
 Springer International Publishing AG
 eBook ISBN
 9783319719375
 DOI
 10.1007/9783319719375
 Hardcover ISBN
 9783319719368
 Softcover ISBN
 9783319891231
 Edition Number
 1
 Number of Pages
 XII, 426
 Number of Illustrations
 446 b/w illustrations, 65 illustrations in colour
 Topics