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  • Book
  • © 2017

Obesity and Brain Function

  • Explores the ways that adipose can affect the brain and central nervous system
  • Contains a chapter on the effects of bariatric surgery on brain function
  • Addresses obesity as a risk factor in many neurological disorders

Part of the book series: Advances in Neurobiology (NEUROBIOL, volume 19)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-viii
  2. Adipose Tissue Biology and Crosstalks

    1. Front Matter

      Pages 1-1
    2. Function and Dysfunction of Adipose Tissue

      • Paulo Matafome, Raquel Seiça
      Pages 3-31
    3. The Role of Brain in Energy Balance

      • Paulo Matafome, Raquel Seiça
      Pages 33-48
    4. Neuroendocrinology of Adipose Tissue and Gut–Brain Axis

      • Paulo Matafome, Hans Eickhoff, Liliana Letra, Raquel Seiça
      Pages 49-70
  3. Obesity as a Risk Factor for Neurological Disease

    1. Front Matter

      Pages 71-71
    2. Hypothalamic Dysfunction in Obesity and Metabolic Disorders

      • Sara Carmo-Silva, Cláudia Cavadas
      Pages 73-116
    3. Diabesity and Brain Energy Metabolism: The Case of Alzheimer’s Disease

      • Susana Cardoso, Raquel Seiça, Paula I. Moreira
      Pages 117-150
    4. Multiple Sclerosis: Implications of Obesity in Neuroinflammation

      • Ana Margarida Novo, Sónia Batista
      Pages 191-210
  4. Brain Function After Bariatric Surgery

    1. Front Matter

      Pages 211-211
  5. Neuroimaging in Obesity

    1. Front Matter

      Pages 237-237
    2. Functional Neuroimaging in Obesity Research

      • Liliana Letra, Daniela Pereira, Miguel Castelo-Branco
      Pages 239-248

About this book

This compendium provides a wide view covering everything from molecular mechanisms and risk factors for neurological disorders to the effects of bariatric surgery on brain function and functional neuroimaging applied to obesity research. The impact of obesity on brain function and the development of neurodegenerative and neuroinflammatory disorders has been understudied, despite the recent proliferation of obesity research. Among the topics covered are adipose biology, the adipose tissue - gut - brain axis, brain energy metabolism, dementia, cerebrovascular disease, and multiple sclerosis.

Editors and Affiliations

  • Institute of Physiology, Institute for Biomedical Imaging and Life Sciences—IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal

    Liliana Letra, Raquel Seiça

About the editors

Liliana Letra received her M.D. and Masters in Medicine from University of Coimbra, Portugal and her Neurology specialization from Centro Hospitalar e Universitário de Coimbra, Portugal. She is clinical neurologist at Centro Hospitalar do Baixo Vouga, Aveiro, Portugal and has a special interest in cognitive disorders. She is also Invited Assistant of Medical Physiology at Faculty of Medicine of University of Coimbra, Portugal. She develops her investigation and PhD Project in the field of obesity and dementia and her research interest is primarily the association of metabolic diseases and cognitive function.

Raquel Seiça received her M.D. and her PhD and Aggregation in Medicine from University of Coimbra, Portugal. She is Full Professor of Physiology-Medicine and Head of the Institute of Physiology at the same University. She is also Investigator of the Institute for Biomedical Imaging and Life Sciences-IBILI-Faculty of Medicine and Collaborator Investigator in the Center for Classical and Humanistic Studies, Faculty of Arts and Humanities, University of Coimbra. Her scientific interests lie in diabetes mellitus and obesity. She is author of 130 peer-reviewed papers, 13 book chapters, 193 peer-reviewed published abstracts and 477 presentations. She supervised 3 post-doctoral projects, 9 PhD Thesis, 36 Master Thesis and 46 Research Program Training.


Bibliographic Information

  • Book Title: Obesity and Brain Function

  • Editors: Liliana Letra, Raquel Seiça

  • Series Title: Advances in Neurobiology

  • DOI: https://doi.org/10.1007/978-3-319-63260-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-63259-9Published: 28 September 2017

  • Softcover ISBN: 978-3-319-87511-8Published: 11 August 2018

  • eBook ISBN: 978-3-319-63260-5Published: 19 September 2017

  • Series ISSN: 2190-5215

  • Series E-ISSN: 2190-5223

  • Edition Number: 1

  • Number of Pages: VIII, 248

  • Number of Illustrations: 1 b/w illustrations, 22 illustrations in colour

  • Topics: Neurosciences, Neurology, Endocrinology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access