Progress in Inflammation Research

MIF Family Cytokines in Innate Immunity and Homeostasis

Editors: Bucala, Richard, Bernhagen, Jürgen (Eds.)

Free Preview
  • Provides a comprehensive synthesis of the state-of-the-art of MIF science
  • Covers role of MIF in immunopathogenesis of different inflammatory, autoimmune, and infectious diseases
  • Provides outlook on MIF-directed therapies
see more benefits

Buy this book

eBook 128,39 €
price for Spain (gross)
  • ISBN 978-3-319-52354-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 166,39 €
price for Spain (gross)
  • ISBN 978-3-319-52352-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 166,39 €
price for Spain (gross)
  • ISBN 978-3-319-84882-2
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, metabolism, and cellular stress responses.  MIF’s molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. New family members, such as D-dopachrome tautomerase, or MIF-2, and the closely homologous genes encoding by parasites have been defined and are being functionally characterized.  MIF directed therapies also are entering clinical testing and ultimately may be applied in a pharmacogenomics manner. This book provides a comprehensive synthesis of the state-of-the-art of MIF science. The intended audience are post-graduate students and researchers in inflammation, innate immunity, immunology, and immunopathology.

About the authors

Richard Bucala, MD PhD; Professor of Medicine, Pathology, and Epidemiology & Public Health at Yale University, School of Medicine, New Haven, CT, USA Jürgen Bernhagen, PhD; Institute of Biochemistry and Molecular Cell Biology, Universitätsklinikum Aachen, RWTH Aachen, Germany

Table of contents (14 chapters)

Table of contents (14 chapters)
  • MIF- and CD74-Dependent Mechanisms

    Pages 1-20

    Becker-Herman, Shirly (et al.)

  • HSP90-Stabilized MIF in Oncogenesis and Cell Growth Control

    Pages 21-42

    Schulz-Heddergott, Ramona (et al.)

  • CD74, MIF and Breast Tumorigenesis: Insights from Recent Large-Scale Tumour Genomics and Proteomics Studies

    Pages 43-57

    Metodiev, Metodi V., Ph.D.

  • MIF-Dependent Regulation of Monocyte/Macrophage Polarization

    Pages 59-76

    Yaddanapudi, Kavitha (et al.)

  • Advances in Understanding the Role of MIF in the Pathogenesis of Autoimmune Diseases

    Pages 77-95

    Nalawade, Saisha A. (et al.)

Buy this book

eBook 128,39 €
price for Spain (gross)
  • ISBN 978-3-319-52354-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 166,39 €
price for Spain (gross)
  • ISBN 978-3-319-52352-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 166,39 €
price for Spain (gross)
  • ISBN 978-3-319-84882-2
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
Loading...

Bibliographic Information

Bibliographic Information
Book Title
MIF Family Cytokines in Innate Immunity and Homeostasis
Editors
  • Richard Bucala
  • Jürgen Bernhagen
Series Title
Progress in Inflammation Research
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-52354-5
DOI
10.1007/978-3-319-52354-5
Hardcover ISBN
978-3-319-52352-1
Softcover ISBN
978-3-319-84882-2
Series ISSN
0379-0363
Edition Number
1
Number of Pages
VIII, 246
Number of Illustrations
12 b/w illustrations, 25 illustrations in colour
Topics