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Cancer Biomarkers in Body Fluids

Biomarkers in Circulation

  • Book
  • © 2017

Overview

  • Presents cancer biomarkers for noninvasive diagnosis of 18 different body fluids

  • Shows prosprectives for a coordinated validation of cancer biomarkers by industries, regulatory bodies, and academics for clinical translation

  • Presents opportunities for cancer personalized medicine ?

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Table of contents (18 chapters)

Keywords

About this book

This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.




Authors and Affiliations

  • Medical Sciences Division Northern Ontario School of Medicine West Campus, Lakehead University, Thunder Bay, Canada

    Gabriel D. Dakubo

About the author

Dr. Gabriel D. Dakubo is an Assistant Professor of Molecular Medicine and Human Anatomy in the Division of Medical Sciences at the Northern Ontario School of Medicine. He received his BSc and MBChB degrees from the University of Ghana, followed by the pursuance of a Postdoctoral research fellowship in Molecular Medicine at the Ottawa Hospital Research Institute, Canada. Dr. Dakubo’s passion is in noninvasive deployment of biomarkers for cancer management. While an expert in mitochondrial genetic alterations in cancer, he also has a keen interest in the inter-genomic communications that occur in the cancer cell, as well as the Slaughter’s concept of field cancerization. Dr. Dakubo is well published, and is a reviewer of a number of esteemed journals, including Clinical Cancer Research.

Bibliographic Information

  • Book Title: Cancer Biomarkers in Body Fluids

  • Book Subtitle: Biomarkers in Circulation

  • Authors: Gabriel D. Dakubo

  • DOI: https://doi.org/10.1007/978-3-319-48360-3

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-48359-7Published: 16 December 2016

  • Softcover ISBN: 978-3-319-83921-9Published: 05 July 2018

  • eBook ISBN: 978-3-319-48360-3Published: 23 November 2016

  • Edition Number: 1

  • Number of Pages: XIX, 509

  • Number of Illustrations: 20 illustrations in colour

  • Topics: Human Genetics, Oncology, Cancer Research

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