Imaging Biomarkers

Development and Clinical Integration

Editors: Martí-Bonmatí, Luis, Alberich-Bayarri, Angel (Eds.)

  • Examines all aspects of the development of imaging biomarkers and their integration into clinical practice
  • Includes practical use cases on imaging biomarker implementation in various fields of medicine
  • Written by a multidisciplinary team of expert radiologists and engineers 
see more benefits

Buy this book

eBook 101,14 €
price for Spain (gross)
  • ISBN 978-3-319-43504-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 124,79 €
price for Spain (gross)
  • ISBN 978-3-319-43502-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 124,79 €
price for Spain (gross)
  • ISBN 978-3-319-82841-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

This is the first book to cover all aspects of the development of imaging biomarkers and their integration into clinical practice, from the conceptual basis through to the technical aspects that need to be considered in order to ensure that medical imaging can serve as a powerful quantification instrument capable of providing valuable information on organ and tissue properties. The process of imaging biomarker development is considered step by step, covering proof of concept, proof of mechanism, image acquisition, image preparation, imaging biomarker analysis and measurement, detection of measurement biases (proof of principle), proof of efficacy and effectiveness, and reporting of results. Sources of uncertainty in the accuracy and precision of measurements and pearls and pitfalls in gold standards and biological correlation are discussed. In addition, practical use cases are included on imaging biomarker implementation in brain, oncologic, cardiovascular, musculoskeletal, and abdominal diseases. The authors are a multidisciplinary team of expert radiologists and engineers, and the book will be of value to all with an interest in the quantitative imaging of biomarkers in personalized medicine.

About the authors

Luis Martí-Bonmatí, MD, PhD

Luis Martí-Bonmatí is radiologist and Chairman of the Clinical Area of Medical Imaging at La Fe Polytechnics and University Hospital in Valencia, Spain. He has been a member of the Executive Council and has served as Director of the Research Committee of the European Society of Radiology (ESR) from 2010 to 2013, starting the Imaging Biomarkers Subcommittee. He is currently a member of the European Imaging Biomarkers Alliance (EIBALL) and of the Scientific Council of the European Institute of Biomedical Imaging Research (EIBIR).  Martí-Bonmatí is author of a high number of publications focused on Magnetic Resonance, Clinical Radiology, the development of Imaging Biomarkers, and Engineering-supported Biomedical Research. He is currently Associate Editor of European Radiology and Radiology journals.

 

Angel Alberich-Bayarri, PhD

Angel Alberich-Bayarri is biomedical engineer and Scientific-Technical Director at the Biomedical Imaging Research Group (GIBI230) at La Fe Polytechnics University Hospital. He has worked in the development of several algorithms for Imaging Biomarkers analysis that promoted the creation of the start-up QUIBIM (Quantitative Imaging Biomarkers in Medicine), focused in the creation of a platform for the analysis of Imaging Biomarkers.  He is member of the board of the European Society of Medical Imaging Informatics (EUSOMII) and of the e-Health and Informatics Subcommittee of the European Society of Radiology (ESR). Alberich-Bayarri is authors of several publications in the field of imaging biomarkers. He received the MIT Innovators Under 35 award in 2015.

Reviews

“This book discusses all the aspects of establishing an imaging biomarker by systemically guiding the reader through the various steps of development.  …  a book that will provide an excellent induction for novices in this field. For someone contemplating developing a new biomarker to measure a disease process of interest, or for industry employees entering the world of monitoring new treatments using biomarkers, this book will be an excellent reading and stimulate further thinking.” (Professor Frederik Barkhof, RAD Magazine, December, 2017)


Table of contents (21 chapters)

  • The Shift in Paradigm to Precision Medicine in Imaging: International Initiatives for the Promotion of Imaging Biomarkers

    Trattnig, Siegfried

    Pages 1-7

    Preview Buy Chapter 30,19 €
  • Introduction to the Stepwise Development of Imaging Biomarkers

    Martí-Bonmatí, Luis

    Pages 9-27

    Preview Buy Chapter 30,19 €
  • Defining the Biological Basis and Clinical Question (Proof of Concept); Looking for the Interrelationship (Proof of Mechanism)

    Bamberg, Fabian (et al.)

    Pages 29-43

    Preview Buy Chapter 30,19 €
  • Image Acquisition: Modality and Protocol Definition

    Sánchez-González, Javier (et al.)

    Pages 45-52

    Preview Buy Chapter 30,19 €
  • MRI Preprocessing

    Manjón, José V.

    Pages 53-63

    Preview Buy Chapter 30,19 €

Buy this book

eBook 101,14 €
price for Spain (gross)
  • ISBN 978-3-319-43504-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 124,79 €
price for Spain (gross)
  • ISBN 978-3-319-43502-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 124,79 €
price for Spain (gross)
  • ISBN 978-3-319-82841-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Imaging Biomarkers
Book Subtitle
Development and Clinical Integration
Editors
  • Luis Martí-Bonmatí
  • Angel Alberich-Bayarri
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-43504-6
DOI
10.1007/978-3-319-43504-6
Hardcover ISBN
978-3-319-43502-2
Softcover ISBN
978-3-319-82841-1
Edition Number
1
Number of Pages
VIII, 316
Number of Illustrations and Tables
29 b/w illustrations, 75 illustrations in colour
Topics