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Current Treatment Options for Fuchs Endothelial Dystrophy

  • Provides step-by-step descriptions of minimally invasive lamellar transplant techniques such as DSAEK and DMEK

  • Offers guidance on the management of complications

  • Examines emerging medical, cell-based approaches to Fuchs endothelial dystrophy

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-viii
  2. Epidemiology and Genetic Basis of Fuchs Endothelial Corneal Dystrophy

    • Guadalupe Villarreal Jr., Laura Kallay, Gustavo Vedana, Albert S. Jun
    Pages 1-16
  3. Optical and Anatomic Changes in Fuchs Endothelial Dystrophy Corneas

    • Katrin Wacker, Jay W. McLaren, Sanjay V. Patel
    Pages 51-71
  4. DMEK Graft Preparation: Eye Bank Perspective and Risk Factors for Preparation Failure

    • Christopher G. Stoeger, Joshua D. Galloway, Zachary M. Mayko, Christopher S. Sáles
    Pages 87-103
  5. Donor-Tissue Splitting and Tissue Storage for DALK and DMEK Surgery

    • Ludwig M. Heindl, Claus Cursiefen
    Pages 105-118
  6. DSAEK and UT-DSAEK in FED: Step-by-Step Approach

    • Elena Albé, Vincenzo Scorcia, Massimo Busin
    Pages 119-132
  7. DSAEK (Not Only) in Asian Eyes: What Glide to Use? Optimised Insertion Techniques

    • Geraint P. Williams, Donald T. H. Tan
    Pages 133-151
  8. DMEK: Step-by-Step Surgical Approach

    • Bindiya Hapani, M. O. Price, F. W. Price Jr
    Pages 165-187
  9. Complications of Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) Surgery

    • P. James Sanchez, Michael D. Straiko, Mark A. Terry
    Pages 189-204
  10. Revision Surgical Options for Failed PK in FED

    • Danny Mitry, Bruce Allan
    Pages 205-212
  11. Immune Reactions and Dry Eye After Posterior Lamellar Keratoplasty

    • Philipp Steven, Sebastian Siebelmann, Deniz Hos, Franziska Bucher, Claus Cursiefen
    Pages 227-235
  12. Tissue Engineering of a Healthy Corneal Endothelium for FECD Patients

    • Isabelle Brunette, Stéphanie Proulx
    Pages 237-255

About this book

This book provides state of the art information on modern minimally invasive lamellar transplant techniques for Fuchs endothelial dystrophy (FED), such as Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK). In addition to clear step-by-step descriptions of procedures, guidance is offered on donor tissue preparation, potential intra- and postoperative complications, and complication management. Future treatment options in the form of medical, cell-based approaches are also discussed. To complete the picture, relevant information is included on the pathophysiology, clinical features, and differential diagnosis of FED. This book will be of interest to all who wish to learn about the dramatic developments in corneal transplantation and medical treatment that are transforming the management of FED.

Reviews

“Current Treatment Options for Fuchs Endothelial Dystrophy (Springer), edited by Claus Cursiefen and Albert S Jun, describes the current state-of-the-art of every current and potential treatment modality for FED. … This book is intended for cornea fellows and cornea specialists who are interested in honing their skills based on the most recent advances in the field.” (EuroTimes, April, 2017)

Editors and Affiliations

  • Department of Ophthalmology, University of Cologne, Cologne, Germany

    Claus Cursiefen

  • Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, USA

    Albert S. Jun

About the editors

Claus Cursiefen, MD, PhD, is Chairman and Professor in the Department of Ophthalmology at the University of Cologne, Germany and Adjunct Associate Scientist with the Schepens Eye Research Institute/Harvard Medical School, Boston. After completing his MD thesis at the Department of Anatomy, University of Würzburg, Dr. Cursiefen undertook a residency in the Department of Ophthalmology, Erlangen and a postdoctoral fellowship at the Schepens Eye Research Institute in Boston, MA. His clinical focus encompasses modern lamellar corneal transplant techniques (DMEK, DALK, DSAEK), artificial cornea, ocular surface reconstruction, cataract and glaucoma surgery, curative and refractive laser surgery, and ophthalmo-oncology. Dr. Cursiefen’s research has concentrated especially on mechanisms of corneal hem- and lymphangiogenesis and their implications for corneal transplant immunology. He is the author of more than 250 publications in the field, including in PNAS, Journal of Experimental Medicine, Journal of Clinical Investigation, and Nature Medicine.

Albert S. Jun, MD, PhD, is a board-certified opththalmologist who works at The Johns Hopkins Hospital, Baltimore, MD, USA,  and is Associate Professor of Ophthalmology at The Johns Hopkins University School of Medicine. He is also Associate Professor of Ophthalmology and Vice Chair for Education at the Wilmer Eye Institute. After gaining his PhD from Emory University Graduate School of Arts and Sciences, focusing on Genetics and Molecular Biology, Dr. Jun completed an Ophthalmology Residency at The Johns Hopkins Medical Institutions (1998–2001), a Cornea and External Disease Fellowship at Moorfields Eye Hospital (London, UK) (2001–2), and a Corneal Gene Therapy Research Fellowship at Imperial College School of Medicine (London, UK) (2002). He became a Diplomate of the  American Board of Ophthalmology in 2003. In 2013 he received an Achievement Award from the American Academy of Ophthalmology and was International Visiting Professor on the occasion of the 150th Anniversary of the Department of Ophthalmology, Medical University of Graz, Austria. More recently he was International Visiting Professor at the Bowman Corneal Club, Liverpool (UK). Dr. Jun is a member of the editorial board of Cornea: The Journal of Cornea and External Disease. He is lead or co-author of approximately 60 peer-reviewed publications.

Bibliographic Information

  • Book Title: Current Treatment Options for Fuchs Endothelial Dystrophy

  • Editors: Claus Cursiefen, Albert S. Jun

  • DOI: https://doi.org/10.1007/978-3-319-43021-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2017

  • Hardcover ISBN: 978-3-319-43019-5Published: 11 November 2016

  • Softcover ISBN: 978-3-319-82717-9Published: 07 July 2018

  • eBook ISBN: 978-3-319-43021-8Published: 31 October 2016

  • Edition Number: 1

  • Number of Pages: VIII, 255

  • Number of Illustrations: 12 b/w illustrations, 59 illustrations in colour

  • Topics: Ophthalmology, Minimally Invasive Surgery

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access