Overview
- Provides systematic and extensive discussion of microRNA's clinical applications
- Chapter authors are distinguished experts in each clinical field and are from prominent universities and institutions
- Focuses on innovative applications of microRNA in developing selective therapies in several disorders and does not focus primarily on cell proliferation and cancer making it somewhat unique among the literature
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 888)
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Table of contents (22 chapters)
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Front Matter
Keywords
About this book
This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters explore the clinical role of microRNAs in the diagnosis and treatment of metabolic and cardiovascular disorders, focusing on mitochondrial fitness, arterial hypertension, cardiovascular remodeling, cerebrovascular disease, pulmonary hypertension, diabetic kidney disease, and kidney transplantation. The subsequent chapters discuss the importance of microRNAs in the wound healing process and in skin disease, in the pathogenesis of allergy, in human ovulation, and in infection. The book concludes with chapters which outline the emerging role of microRNAS in doping and detail microRNA profiling.
microRNA: Medical Evidence is an ideal companion to both microRNA: Basic Scienceand microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the
molecular level to clinical
practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.Editors and Affiliations
About the editor
Dr. Gaetano Santulli received his MD and PhD at the University of Naples “Federico II”. A physician scientist, Dr. Santulli completed his postdoctoral training at Columbia University Medical Center in New York City, supported by an AHA fellowship and a Scientist Development Grant. Cardiologist, he authored more than 100 publications, including peer-reviewed articles in high impact journals, book chapters, and medical books. He is currently a faculty member of Columbia University. He lives in Manhattan.
Dr. Santulli’s expertise comprises both clinical and basic research topics, including hypertension, diabetes, angiogenesis, heart failure, arrhythmias, vascular disorders, and skeletal muscle disease. He is a member of several international academic societies, including New York Academy of Sciences, American Heart Association (AHA), American Diabetes Association, European Society of Cardiology, Endocrine Society, American Association for the Advancement of Science, European Association of Heart Failure, European Association of Echocardiography, Acute Cardiovascular Care Association, European Association of Percutaneous Cardiovascular Interventions. He serves on the Editorial Boards of numerous medical Journals.
Bibliographic Information
Book Title: microRNA: Medical Evidence
Book Subtitle: From Molecular Biology to Clinical Practice
Editors: Gaetano Santulli
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-319-22671-2
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2015
Hardcover ISBN: 978-3-319-22670-5Published: 21 December 2015
Softcover ISBN: 978-3-319-79416-7Published: 16 March 2019
eBook ISBN: 978-3-319-22671-2Published: 11 December 2015
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XIII, 429
Number of Illustrations: 10 b/w illustrations, 26 illustrations in colour
Topics: Molecular Medicine, Cell Physiology, Atomic/Molecular Structure and Spectra, Animal Biochemistry, Human Physiology