Overview
- Summarizes and discusses current advancements in T cell-based anticancer immunotherapy
- Comprehensively covers T cell biology, including T cell lineage differentiation stages, mechanisms of anergy and activation, exhaustion, senescence, stemness, and strategies of deregulation for therapeutic development
- Explores novel approach of hematopoietic stem cell transplantation as a method of immune therapy for cancer
Part of the book series: Cancer Drug Discovery and Development (CDD&D)
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Table of contents(14 chapters)
About this book
Editors and Affiliations
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Unit of Melanoma & Cancer Immunotherapy, National Tumor Institute Fondazione G., Naples, Italy
Paolo A. Ascierto
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Department of Transfusion Medicine, National Institutes of Health, Bethesda, USA
David F. Stroncek
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Department of Transfusion Medicine, National Institutes of Health, BETHESDA, USA
Ena Wang
About the editors
Ena Wang, MD, is Director of Molecular Science, Infectious Diseases and Immunogenetics Section at the National Institutes of Health. The focus of her research is the identification of genetic traits in humans that could explain the relationship between pathogens and the host with particular interest in cancer and chronic infections During her career at NIH, Dr. Wang was twice granted the Investigator Travel Fellowship Award; received an NIH Bench-to-Bedside Award in 2002; received the Minority Award as a mentor and principle investigator in 2002; received the NCI Director’s 2006 Intramural Innovation Award as co-investigator in 2006; and received the Clinic Center Director’s Award for scientific excellence in 2007. Dr. Wang has authored 17 book chapters and published more than 130 peer reviewed articles. Her scientific papers have received more than 6,500 citations.
Paolo Antonio Ascierto, MD, is Vice Director of the Unit of Melanoma, Cancer Immunotherapy and Innovative Therapy at the National Institute Fondazione G. Pascale in Naples, Italy. Dr. Ascierto has published more than 117 scientific papers, which have received more than 2,100 citations.
David F. Stroncek, MD, is the Chief of the Cell Processing Section at the Department of Transfusion Medicine at the National Institutes of Health. Dr. Stroncek has published more than 264 scientific papers, which have received more than 5,300 citations.
Bibliographic Information
Book Title: Developments in T Cell Based Cancer Immunotherapies
Editors: Paolo A. Ascierto, David F. Stroncek, Ena Wang
Series Title: Cancer Drug Discovery and Development
DOI: https://doi.org/10.1007/978-3-319-21167-1
Publisher: Humana Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing Switzerland 2015
Hardcover ISBN: 978-3-319-21166-4Published: 04 December 2015
Softcover ISBN: 978-3-319-79330-6Published: 14 March 2019
eBook ISBN: 978-3-319-21167-1Published: 26 November 2015
Series ISSN: 2196-9906
Series E-ISSN: 2196-9914
Edition Number: 1
Number of Pages: XV, 305
Number of Illustrations: 26 illustrations in colour
Topics: Cancer Research, Immunology, Molecular Medicine, Cell Biology