Overview
Provides a comprehensive overview of the role of TRP channels in processing sensory information
Examines photo transduction, chemotransduction, mechanotransduction, thermotransduction and pain
Contributing authors are investigators whose research has contributed significantly to the understanding of TRP channels and the senses
Includes supplementary material: sn.pub/extras
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Table of contents (10 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Reviews
“This is a good monograph on ion channels in cell receptors of Drosophila & C Elegans. … I highly recommend this book to all readers with interests in physiology and cell biology.” (Joseph J. Grenier, Amazon.com, September, 2015)
Editors and Affiliations
About the editors
Juan Bacigalupo, born in Santiago, Chile, did his undergraduate in Biology at the Universidad de Chile, after which he obtained a position in the same university. He was trained in electrophysiology and biophysics in the renowned Laboratory of Montemar, Chile. He moved to Brandeis University (USA) for his doctoral studies. In this work he pioneered the patch clamp studies of single-channel currents in sensory receptor cells, working on Limulus photoreceptors. He then returned to Chile, focusing his research on the molecular and cellular bases of several modalities of sensory transduction as well as other aspects of sensory physiology and biophysics. He uses a variety of multidisciplinary tools, of which recording unitary transduction channel currents directly from sensory cilia and microvilli has been particularly successful in exploring the physiology of these highly specialized organelles, and represents a seal of his laboratory. He has been awarded a Guggenheim Foundation Fellowship, a Presidential Chair in Science (Chile) and is President of the Chilean Society for Neuroscience.
Rodolfo Madrid was born in Santiago, Chile. He did his PhD thesis with Juan Bacigalupo at the Universidad de Chile, where he was trained in electrophysiology, biophysics and sensory physiology. After a post-doctorate at the University of Washington, he moved to the Instituto de Neurociencias de Alicante. He contributed to unveil the role of the thermoTRP channel TRPM8 and Kv1 potas
sium channels in cold sensitivity and excitability of primary sensory neurons of the somatosensory system. He returned to Chile in 2008, where he settled his own laboratory at the Universidad de Santiago de Chile, focusing his research on the study of the molecular and cellular bases of thermotransduction and nociception, the role of TRP channels and other voltage-sensitive channels in sensory physiology, as well as biophysics of thermoTRP channels. He uses multidisciplinary approaches that include patch clamping of primary sensory neurons, calcium imaging, extracellular recording of thermoreceptors and nociceptors ex vivo and molecular and cell biology tools. He is Associate Professor of the Faculty of Chemistry and Biology of the Universidad de Santiago de Chile and Director of the Doctoral Program in Neuroscience of this University.Bibliographic Information
Book Title: TRP Channels in Sensory Transduction
Editors: Rodolfo Madrid, Juan Bacigalupo
DOI: https://doi.org/10.1007/978-3-319-18705-1
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2015
Hardcover ISBN: 978-3-319-18704-4Published: 03 September 2015
Softcover ISBN: 978-3-319-34560-4Published: 22 October 2016
eBook ISBN: 978-3-319-18705-1Published: 24 August 2015
Edition Number: 1
Number of Pages: X, 234
Number of Illustrations: 10 b/w illustrations, 23 illustrations in colour
Topics: Neurosciences, Human Physiology, Neurobiology