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SpringerBriefs in Pharmaceutical Science & Drug Development

Lipid Nanoparticles: Production, Characterization and Stability

Authors: Shah, R., Eldridge, D., Palombo, E., Harding, I.

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  • One of the few works written on lipid nanoparticles
  • Extensive description of the characterization, manufacture and stability of lipid nanoparticles
  • Clear description of how lipid nanoparticles can be used as drug carriers
  • An illustrative and clear approach to understanding lipid nanoparticles production
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eBook 44,02 €
price for Spain (gross)
  • ISBN 978-3-319-10711-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 57,19 €
price for Spain (gross)
  • ISBN 978-3-319-10710-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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About this book

​What are lipid nanoparticles?  How are they structured?  How are they formed? What techniques are best to characterize them?  How great is their potential as drug delivery systems?  These questions and more are answered in this comprehensive and highly readable work on lipid nanoparticles. This work sets out to provide the reader with a clear and understandable understanding of the current practices in formulation, characterization and drug delivery of lipid nanoparticles. A comprehensive description of the current understanding of synthesis, characterization, stability optimization and drug incorporation of solid lipid nanoparticles is provided. Nanoparticles have attracted great interest over the past few decades with almost exponential growth in their research and application. Their small particle size and subsequent high surface area make them ideal in many uses, but particularly as drug carrier systems. Nanoparticles made from lipids are especially attractive because of their enhanced biocompatibility imparted by the lipid. The work provides a detailed description of the types of lipid nanoparticles available (e.g. SLN, NLC, LDC, PLN) and how they range from imperfect crystalline to amorphous in structure. Current thoughts on where drugs are situated (e.g. in the core, or at the interface) and how this can be manipulated are discussed.  The many techniques for production, including the author’s own variant of microwave heating, are fully discussed. Techniques for measuring arguably the most important characteristics of particle size and polydispersity are discussed, along with techniques to measure crystallinity, shape and drug capacity.  Finally, a full chapter on techniques for measuring stability, both in the absence and presence of drugs, is discussed, along with suggestions on how to optimize that stability. This work appeals to students of colloid science, practitioners of research into drug delivery and academics alike.

Table of contents (5 chapters)

Table of contents (5 chapters)

Buy this book

eBook 44,02 €
price for Spain (gross)
  • ISBN 978-3-319-10711-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 57,19 €
price for Spain (gross)
  • ISBN 978-3-319-10710-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Rent the eBook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Lipid Nanoparticles: Production, Characterization and Stability
Authors
Series Title
SpringerBriefs in Pharmaceutical Science & Drug Development
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
The Author(s)
eBook ISBN
978-3-319-10711-0
DOI
10.1007/978-3-319-10711-0
Softcover ISBN
978-3-319-10710-3
Series ISSN
1864-8118
Edition Number
1
Number of Pages
IX, 97
Number of Illustrations
12 b/w illustrations, 18 illustrations in colour
Topics