- Describes molecular aspects of the aging immune system
- Discusses new therapeutic approaches
- Written by internationally reputed scientists
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- About this book
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As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses have a strong clinical impact. Improving our understanding of the aged immune system is crucial in developing effective prevention and treatment programs that will facilitate healthy aging and improve the quality of life of the elderly population.
The aim of this volume is to summarize current knowledge on the cellular and molecular aspects of the aging immune system, with an emphasis on infectious diseases and new therapeutic approaches.
- Table of contents (10 chapters)
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Regulation of Adaptive Immunity in the Elderly
Pages 1-23
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Does Innate Immunity Get Old?
Pages 25-36
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Thy(–im)munosenescence: The Ageing of the Thymus and Its Impact on the Immune System
Pages 37-54
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Characteristics of B Cells and B Cell Responses in Aged Individuals
Pages 55-84
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Mechanisms of Immune Protection to Pneumococcal Infection in the Young and the Elderly
Pages 85-126
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Table of contents (10 chapters)
- Download Preface 1 PDF (21.1 KB)
- Download Sample pages 1 PDF (104 KB)
- Download Table of contents PDF (22.9 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Immunosenescence
- Editors
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- Andreas Thiel
- Series Title
- Birkhäuser Advances in Infectious Diseases
- Copyright
- 2012
- Publisher
- Springer Basel
- Copyright Holder
- Springer Basel AG
- eBook ISBN
- 978-3-0346-0219-8
- DOI
- 10.1007/978-3-0346-0219-8
- Hardcover ISBN
- 978-3-0346-0218-1
- Softcover ISBN
- 978-3-0348-0778-4
- Series ISSN
- 2504-3811
- Edition Number
- 1
- Number of Pages
- XVIII, 238
- Topics
