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Clinical Nuclear Medicine in Neurology

An Atlas of Challenging Cases

  • Presents a range of challenging cases in neurology
  • Explores nuclear medicine expertise in single cases
  • Written by respected experts on neuroimaging

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Table of contents (39 chapters)

  1. Front Matter

    Pages i-ix
  2. Nuclear Medicine Cases of Dementia and Movement Disorders

    1. Front Matter

      Pages 1-1
    2. Case 1: Mild Cognitive Impairment (MCI)—[18F]FDG and Amyloid PET

      • Silvia Morbelli, Alberto Miceli
      Pages 3-7
    3. Case 2: Alzheimer’s Disease—[18F]FDG, Tau, and Amyloid PET

      • Javier Arbizu, Juan Fernando Bastidas
      Pages 9-13
    4. Case 3: Alzheimer’s Disease—Behavioral Variant

      • Silvia Morbelli, Matteo Pardini, Flavio Nobili
      Pages 15-18
    5. Case 5: Parkinson’s Disease with Vascular Abnormalities

      • Elsmarieke van de Giessen
      Pages 25-29
    6. Case 6: Parkinson’s Disease with Left-Sided Spasticity

      • Elsmarieke van de Giessen
      Pages 31-34
    7. Case 7: Holmes Tremor

      • Tatiana Horowitz, Eric Guedj
      Pages 35-37
    8. Case 8: Multiple System Atrophy with DAT SPECT and [18F]FDG PET

      • Silvia Morbelli, Dario Arnaldi
      Pages 39-43
    9. Case 10: Progressive Supranuclear Palsy (PSP)

      • Silvia Morbelli, Maria Isabella Donegani
      Pages 51-54
    10. Case 11: Corticobasal Syndrome: [18F]FDG and Amyloid PET

      • Javier Arbizu, Gloria Martí-Andres
      Pages 55-58
    11. Case 12: Huntington’s Disease with Atypical Onset

      • Silvia Morbelli, Giulia Ferrarazzo
      Pages 59-63
    12. Case 13: Huntington’s Disease with Psychiatric Onset

      • Silvia Morbelli, Matteo Bauckneht
      Pages 65-68
    13. Case 14: Creutzfeldt–Jakob Disease with Pathological Confirmation

      • Javier Arbizu, Juan Jose Rosales
      Pages 69-73
  3. Nuclear Medicine Cases of Epilepsy and Encephalitis

    1. Front Matter

      Pages 75-75
    2. Case 15: Non-lesional Temporal Epilepsy

      • Valentina Garibotto, Maria Isabel Vargas, John O. Prior, Andrea O. Rossetti, Serge Vulliemoz, Margitta Seeck
      Pages 77-81
    3. Case 16: Ictal [18F]FDG PET Imaging

      • Valentina Garibotto, Christian Korff, Maria Isabel Vargas, Serge Vulliemoz, Margitta Seeck
      Pages 83-85
    4. Case 17: Focal Refractory Epilepsy with Negative MRI

      • Stanislas Lagarde, Tatiana Horowitz, Eric Guedj
      Pages 87-90

About this book

This book gathers a collection of cases with challenging diagnoses, in which nuclear medicine examinations have been particularly helpful in terms of the final diagnosis or follow-up. The cases presented chiefly involve patients with neurodegenerative disorders, epilepsy and brain tumors. The book is intended for nuclear medicine specialists as well as clinicians, offering essential guidance on the interpretation of neurology cases in the clinical setting, particularly with regard to correctly interpreting diagnostic imaging procedures. The authors were selected from the members of the Neuroimaging Committee of the EANM and have extensive experience as clinicians and teachers within the Nuclear Medicine Community.  


Reviews

“The great interest of this book derives from the fact that, in 200 pages enriched by 100 figures, it analyzes a myriad of exemplary challenging cases in which diagnostic neuroimaging, based on optimized user-independent methods, allowed a correct final diagnosis. … I strongly suggest the acquisition of this publication not only to nuclear physicians and neuro-radiologists but also to all the professionals interested to better understand cerebral diseases. I believe that this book should be present in all the libraries of departments dealing with the brain.” (Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, January 13, 2022)

Editors and Affiliations

  • Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm, Sweden

    Andrea Varrone

  • Nuclear Medicine Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy

    Silvia Morbelli

  • Geneva University and Geneva University Hospitals, Geneva, Switzerland

    Valentina Garibotto

About the editors

Andrea Varrone is a Specialist in Nuclear Medicine and holds a PhD in Functional Radioisotopic Imaging. He is also an Associate Professor of Nuclear Medicine and Research Group Leader for Molecular Imaging in Neurodegenerative Disorders, with affiliation to the Department of Clinical Neuroscience at Karolinska Institutet. Dr. Varrone is an expert on PET imaging for patients with movement disorders. He his currently employed at H. Lundbeck A/S, Valby, Denmark.

Valentina Garibotto is a Specialist in Nuclear Medicine, currently working as a Senior Physician at the Geneva University Hospitals and group leader of the Neuroimaging and Innovative Molecular Tracer Laboratory at Geneva University. Prof. Garibotto has extensive clinical expertise in molecular neuroimaging and has coordinated multiple clinical trials on the validation of novel PET tracers for the diagnostic assessment and physiopathological investigation of cognitive disturbances.

Silvia Morbelli is an Associate Professor of Nuclear Medicine at the University of Genoa and is currently working at San Martino University Hospital. She holds a PhD in Applied Neurosciences and has made valuable contributions concerning the use of neuroimaging tools as diagnostic and prognostic biomarkers in the earliest and preclinical stages of Neurodegenerative Dementia and Parkinsonian Syndromes. She is currently the Chair of the Neuroimaging Committee, European Association of Nuclear Medicine.


Bibliographic Information

  • Book Title: Clinical Nuclear Medicine in Neurology

  • Book Subtitle: An Atlas of Challenging Cases

  • Editors: Andrea Varrone, Silvia Morbelli, Valentina Garibotto

  • DOI: https://doi.org/10.1007/978-3-030-83598-9

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-030-83597-2Published: 11 November 2021

  • Softcover ISBN: 978-3-030-83600-9Published: 12 November 2022

  • eBook ISBN: 978-3-030-83598-9Published: 10 November 2021

  • Edition Number: 1

  • Number of Pages: IX, 202

  • Number of Illustrations: 6 b/w illustrations, 102 illustrations in colour

  • Topics: Nuclear Medicine, Neurology, Oncology

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access