Progress in the Chemistry of Organic Natural Products

Progress in the Chemistry of Organic Natural Products 115

Editors: Kinghorn, A.D., Falk, H., Gibbons, S., Asakawa, Y., Liu, J.-K., Dirsch, V.M. (Eds.)

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About this book

This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

Table of contents (4 chapters)

Table of contents (4 chapters)
  • The Role of Total Synthesis in Structure Revision and Elucidation of Decanolides (Nonanolides)

    Pages 1-57

    Schmidt, Bernd

  • From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development

    Pages 59-114

    Christensen, Søren Brøgger (et al.)

  • Antileishmanial Activity of Lignans, Neolignans, and Other Plant Phenols

    Pages 115-176

    Pospíšil, Jiří (et al.)

  • Recent Advances in the Chemistry and Pharmacology of Cryptolepine

    Pages 177-203

    Shnyder, Steven D. (et al.)

Buy this book

eBook 213,99 €
price for Spain (gross)
  • ISBN 978-3-030-64853-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 259,99 €
price for Spain (gross)
  • ISBN 978-3-030-64852-7
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Progress in the Chemistry of Organic Natural Products 115
Editors
  • A. Douglas Kinghorn
  • Heinz Falk
  • Simon Gibbons
  • Yoshinori Asakawa
  • Ji-Kai Liu
  • Verena M Dirsch
Series Title
Progress in the Chemistry of Organic Natural Products
Series Volume
115
Copyright
2021
Publisher
Springer International Publishing
Copyright Holder
The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG
eBook ISBN
978-3-030-64853-4
DOI
10.1007/978-3-030-64853-4
Hardcover ISBN
978-3-030-64852-7
Series ISSN
2191-7043
Edition Number
1
Number of Pages
VII, 203
Number of Illustrations
101 b/w illustrations, 26 illustrations in colour
Topics