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Application and Integration of Omics-powered Diagnostics in Clinical and Public Health Microbiology

  • Book
  • © 2021

Overview

Editors:
  1. Jacob Moran-Gilad

    1. Ben-Gurion University of the Negev, Beer Sheva, Israel

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Yael Yagel

    1. Ben-Gurion University of the Negev, Beer-Sheva, Israel

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Discusses "omics" technology from a holistic, clinical point-of-view

  • Provides explanation of numerous types of omics technology

  • Cutting-edge resource edited by and featuring contributions from field-leading researchers and practitioners

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-vi
    Download chapter PDF

  2. Introduction to Advanced Diagnostics in Microbiology

    • Yael Yagel, Jacob Moran-Gilad
    Pages 1-7

  3. Overview of Microbial NGS for Clinical and Public Health Microbiology

    • Natacha Couto, John W. Rossen
    Pages 9-24

  4. WGS for Bacterial Identification and Susceptibility Testing in the Clinical Lab

    • Sophia Vourli, Fanourios Kontos, Spyridon Pournaras
    Pages 25-44

  5. Whole-Genome Sequencing for Bacterial Virulence Assessment

    • Florian Tagini, Trestan Pillonel, Gilbert Greub
    Pages 45-68

  6. Epidemiological Typing Using WGS

    • Lieke B. van Alphen, Christian J. H. von Wintersdorff, Paul H. M. Savelkoul
    Pages 69-87

  7. Next-Generation Sequencing in Clinical Virology

    • Anneloes van Rijn-Klink, Jutte J. C. De Vries, Eric C. J. Claas
    Pages 89-110

  8. Metagenomic Applications for Infectious Disease Testing in Clinical Laboratories

    • Laura Filkins, Robert Schlaberg
    Pages 111-131

  9. Integrating Metagenomics in the Routine Lab

    • Etienne Ruppé, Yannick Charretier, Vladimir Lazarevic, Jacques Schrenzel
    Pages 133-152

  10. Advanced Applications of MALDI-TOF MS – Typing and Beyond

    • Aline Cuénod, Adrian Egli
    Pages 153-173

  11. Advanced Applications of MALDI-TOF: Identification and Antibiotic Susceptibility Testing

    • Belén Rodríguez-Sánchez, Marina Oviaño
    Pages 175-189

  12. Fourier Transform Infrared Spectroscopy (FT-IR) for Food and Water Microbiology

    • Ângela Novais, Luísa Peixe
    Pages 191-217

  13. Omics for Forensic and Post-Mortem Microbiology

    • Amparo Fernández-Rodríguez, Fernando González-Candelas, Natasha Arora
    Pages 219-240
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Keywords

About this book

Various “omics” methods have recently revolutionized molecular diagnostics. Next-generation sequencing (NGS) makes it possible to sequence a human genome in just one day. Whole genome sequencing (WGS) greatly improves the ability to investigate the outbreaks of numerous pathogens. Metagenomics helps to analyze the microbiome, which aids greatly in identifying the pathogenesis of infectious diseases. Proteomic-based methods, namely matrix-assisted laser desorption-ionization time of flight mass spectrometry (MALDI-TOF-MS), have a promising role in identifying myctobacteria and fungi, and predicting antimicrobial resistance.

While there are numerous scientific publications on “omics” applications for microbiology, there are relatively few books that review this topic from a clinical diagnostics perspective. This book looks at this field from a holistic viewpoint, instead of limiting by type of “omics” technology, in order to cover the body of knowledge needed for practitioners and academics interested in clinical and public health microbiology. Additionally, it addresses the management, economical, regulatory and operational aspects of integrating these technologies into routine diagnostics.

Editors and Affiliations

  • Ben-Gurion University of the Negev, Beer Sheva, Israel

    Jacob Moran-Gilad

  • Ben-Gurion University of the Negev, Beer-Sheva, Israel

    Yael Yagel

About the editors

Dr. Jacob Moran-GiladDepartment of Health Systems Management, Faculty of Health Sciences
Ben-Gurion University 
Israel


Dr. Yael Yagel
Department of Health Systems Management
Ben-Gurion University
Israel

Bibliographic Information

  • Book Title: Application and Integration of Omics-powered Diagnostics in Clinical and Public Health Microbiology

  • Editors: Jacob Moran-Gilad, Yael Yagel

  • DOI: https://doi.org/10.1007/978-3-030-62155-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-62154-4Published: 04 June 2021

  • Softcover ISBN: 978-3-030-62157-5Published: 05 June 2022

  • eBook ISBN: 978-3-030-62155-1Published: 24 May 2021

  • Edition Number: 1

  • Number of Pages: VI, 240

  • Number of Illustrations: 2 b/w illustrations, 15 illustrations in colour

  • Topics: Molecular Medicine, Infectious Diseases, Genetics and Genomics, Immunology

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