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Brain Network Dysfunction in Neuropsychiatric Illness

Methods, Applications, and Implications

Editors: Diwadkar, Vaibhav A., Eickhoff, Simon (Eds.)

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  • Combines and synthesizes expertise from neuroimaging and psychiatry
  • Discusses applications of neuroimaging to reveal dysfunctional brain networks interactions in specific neuropsychiatric disorders
  • Explores the implications of research findings for understanding the mechanistic bases of various diseases and for their management and treatment
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eBook 179,99 €
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  • ISBN 978-3-030-59797-9
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Hardcover 228,79 €
price for Spain (gross)
  • ISBN 978-3-030-59796-2
  • Free shipping for individuals worldwide
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  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

Brain network function and dysfunction is the dominant model for understanding how the brain gives rise to normal and abnormal behavior. Moreover, neuropsychiatric illnesses continue to resist attempts to reveal an understanding of their bases. Thus, this timely volume provides a synthesis of the uses of multiple analytic methods as they are applied to neuroimaging data, to seek understanding of the neurobiological bases of psychiatric illnesses, understanding that can subsequently aid in their management and treatment. A principle focus is on the analyses and application of methods to functional magnetic resonance imaging (fMRI) data. fMRI remains the most widely used neuroimaging technique for estimating brain network function, and several of the methods covered can estimate brain network dysfunction in resting and task-active states.

Additional chapters provide details on how these methods are (and can be) applied in the understanding of several neuropsychiatric disorders, including schizophrenia, mood disorders, autism, borderline personality disorder, and attention deficit hyperactivity disorder (ADHD). A final complement of chapters provides a collective overview of how this framework continues to provoke theoretical advances in our conception of the brain in psychiatry. This unique volume is designed to be a comprehensive resource for imaging researchers interested in psychiatry, and for psychiatrists interested in advanced imaging applications.

About the authors

Dr. Vaibhav Diwadkar is Professor of Psychiatry & Behavioral Neurosciences at Wayne State University School of Medicine. He received his B.A. in Psychology and Computer Science from Coe College, and his PhD in Psychology and Cognitive Science from Vanderbilt University. Following neuroimaging-related fellowships at Carnegie Mellon University and the University of Pittsburgh, he has served on the faculty of the University of Pittsburgh, and at Wayne State University where he has been since 2005. He uses in vivo neuroimaging to understand mechanisms of brain network function (underlying psychological and physiological processes), publishing in the areas of learning, memory, cognition and sensorimotor function, and thermoregulation. His clinical neuroimaging interests lie in understanding brain network dysfunction in psychiatry, leading to publications on schizophrenia, mood disorders, obsessive compulsive disorder, and borderline personality disorder. His research is supported by the National Institutes of Mental Health, the Children's Research Center of Michigan, the Children’s Hospital of Michigan Foundation, the Ethel and James Flinn Foundation, the DMC Foundation, the Cohen Neuroscience Endowment, the Prechter World Bipolar Foundation, the Jack Dorsey Endowment, and the National Alliance for Research on Schizophrenia and Depression (now the Brain and Behavior Research Foundation).


Simon Eickhoff is a full professor and chair of the Institute for Systems Neuroscience at the Heinrich-Heine University in Düsseldorf and the director of the Institute of Neuroscience and Medicine (INM-7, Brain and Behavior) at the Forschungszentrum Jülich. He is furthermore a visiting professor at the Chinese Academy of Science Institute of Automation. Workig at the interface between neuroanatomy, data-science and brain medicine, the he aims to obtain a more detailed characterization of the organization of the human brain and its inter-individual variability in order to better understand its changes in advanced age as well as neurological and psychiatric disorders. This goal is pursued by the development and application of novel analysis tools and approaches for large-scale, multi-modal analysis of brain structure, function and connectivity as well as by machine-learning for single subject prediction of cognitive and socio-affective traits and ultimately precision medicine.

Table of contents (22 chapters)

Table of contents (22 chapters)
  • Brain Network Dysconnection in Neuropsychiatric Disorders: The Practice of “Normal Science”

    Pages 1-15

    Diwadkar, Vaibhav A. (et al.)

  • fMRI: Blood Oxygen Level-Dependent Contrast and Its Value for Understanding Functional Brain Networks

    Pages 19-44

    Bandettini, Peter A.

  • Review of Resting-State Functional Connectivity Methods and Application in Clinical Populations

    Pages 45-74

    Karunakaran, Keerthana (et al.)

  • Directed Interregional Brain Interactions

    Pages 75-92

    Bressler, Steven L.

  • Meta-Analytic Connectivity Modelling (MACM): A Tool for Assessing Region-Specific Functional Connectivity Patterns in Task-Constrained States

    Pages 93-104

    Langner, Robert (et al.)

Buy this book

eBook 179,99 €
price for Spain (gross)
  • ISBN 978-3-030-59797-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 228,79 €
price for Spain (gross)
  • ISBN 978-3-030-59796-2
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Brain Network Dysfunction in Neuropsychiatric Illness
Book Subtitle
Methods, Applications, and Implications
Editors
  • Vaibhav A. Diwadkar
  • Simon Eickhoff
Copyright
2021
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-59797-9
DOI
10.1007/978-3-030-59797-9
Hardcover ISBN
978-3-030-59796-2
Edition Number
1
Number of Pages
XVII, 488
Number of Illustrations
7 b/w illustrations, 72 illustrations in colour
Topics